Human CD 59 ELISA Kit ELISA试剂盒,Human CD 59 ELISA Kit/人CD 59 ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Human CD 59 ELISA Kit ELISA试剂盒,Human CD 59 ELISA Kit/人CD 59 ELISA试剂盒

2024-10-24

Human CD 59 ELISA Kit/人CD 59 ELISA试剂盒

货号：EH76RB,EH76RBX5,EH76RBX10

规格：96 tests,5X96 tests,10X96 tests

价格：6641,29884,57271

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：人

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	40 pg/mL
检测范围	40-10,000 pg/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	CD59
Protein aliases	1F5 antigen, 20 kDa homologous restriction factor, CD59, CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344), CD59 glycoprotein, CD59 molecule, complement regulatory protein, HRF-20, human leukocyte antigen MIC11, Ly-6-like protein, lymphocytic antigen CD59/MEM43, MAC-inhibitory protein, MAC-IP, MACIF, MEM43 antigen, membrane attack complex (MAC) inhibition factor, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIRL, Protectin, surface anitgen recognized by monoclonal antibody 16.3A5, T cell-activating protein
物种（Tested）	人
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	16.3A5, 1F5, CD59, EJ16, EJ30, EL32, G344, HRF-20, HRF20, MAC-IP, MACIF, MEM43, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20
Gene ID	(Human) 966
Gene symbol	CD59
UniProt ID	(Human) P13987

Human CD 59 quantitates human CD 59 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CD 59.人CD 59定量分析血清，血浆，上清液中的人CD 59。该检测试剂盒将专门识别天然和重组人CD 59。Target information 靶标信息CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). CD59 is the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 also associates with C5b-8 complex and counteracts appropriate formation of cytolytic pore within the plasma membrane. Further, CD59 is a low-affinity ligand of human CD2, causes T cell costimulation, and is involved in lymphocyte signal transduction. CD59 is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. Mutations in this gene cause CD59 deficiency, a disease involving hemolytic anemia, thrombosis, and cerebral infarction. Multiple alternatively spliced transcript variants of CD59 have been identified.CD59（Protectin）是一种小的（18-20 kDa）GPI锚定膜表达复合物（MAC）遍在表达的抑制剂。 CD59是从补体级联的末端效应子机制中保护自体细胞的关键调节剂。 CD59还与C5b-8复合物缔合，并抵消了质膜内溶细胞孔的适当形成。此外，CD59是人CD2的低亲和力配体，引起T细胞共刺激，并参与淋巴细胞信号转导。 CD59是补体膜攻击复合物的有效抑制剂，因此在该复合物组装过程中，CD59与补体C8和/或C9结合，从而抑制了C9的多个拷贝掺入复合物中，这是渗透孔形成所必需的。该基因的突变导致CD59缺乏症，一种涉及溶血性贫血，血栓形成和脑梗塞的疾病。已经鉴定出CD59的多个选择性剪接的转录变体。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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Human CD 59 ELISA Kit ELISA试剂盒,Human CD 59 ELISA Kit/人CD 59 ELISA试剂盒

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