Human CD 74 ELISA Kit ELISA试剂盒,Human CD 74 ELISA Kit/人CD 74 ELISA试剂盒

2024-10-24

Human CD 74 ELISA Kit/人CD 74 ELISA试剂盒

货号:EH77RB,EH77RBX5,EH77RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.1 ng/mL

检测范围0.10-25 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameCD74
Protein aliasesCD74, CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated), CD74 molecule, major histocompatibility complex, class II invariant chain, gamma chain of class II antigens, HLA class II histocompatibility antigen gamma chain, HLA-DR antigens-associated invariant chain, HLA-DR-gamma, Ia antigen-associated invariant chain, Ia-associated invariant chain, Ii, MHC HLA-DR gamma chain, p33

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesCD74, DHLAG, HLADG, Ia-GAMMA, II
Gene ID(Human) 972
Gene symbolCD74
UniProt ID(Human) P04233
Human CD 74 quantitates human CD 74 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CD 74.人CD 74定量测定血清,血浆,上清液中的人CD 74。该检测试剂盒将专门识别天然和重组人CD 74。Target information 靶标信息HLA-DR, like other MHC class II molecules, is a transmembrane glycoprotein composed of a 36 kDa alpha chain (DRA) and 27 kDa beta chain (DRB). The alpha chain gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. HLA-DR is expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells and activated T lymphocytes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides, present them to T-helper cells, and have a critical role in the initiation of the immune response.像其他MHC II类分子一样,HLA-DR是一种跨膜糖蛋白,由36 kDa的α链(DRA)和27 kDa的β链(DRB)组成。 α链基因包含5个外显子。外显子1编码前导肽,外显子2和3编码两个胞外域,外显子4编码跨膜域和胞质尾。 DRA在肽结合部分没有多态性,并充当DRB1,DRB3,DRB4和DRB5的唯一α链。在DR分子中,β链包含所有指定多肽结合特异性的多态性。已经描述了数百种DRB1等位基因,这些基因多态性的分型通常用于骨髓和肾脏移植。 HLA-DR主要在抗原呈递细胞上表达,例如B淋巴细胞,单核细胞,巨噬细胞,胸腺上皮细胞和活化的T淋巴细胞。 DR,DQ和DP这三个基因座编码人类II类区域的主要表达产物。人MHC II类分子结合细胞内加工的肽,将其呈递给T辅助细胞,并在引发免疫反应中起关键作用。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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