Human CD21/CR2/EBV receptor ELISA Kit ELISA试剂盒,Human CD21/CR2/EBV receptor ELISA Kit/人CD21 / CR2 / EBV受体ELISA试剂盒

2024-10-24

Human CD21/CR2/EBV receptor ELISA Kit/人CD21 / CR2 / EBV受体ELISA试剂盒

货号:EH81RB,EH81RBX5,EH81RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

17 pg/mL

检测范围17-4,000 pg/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameCD21
Protein aliasesCD21, Complement C3d receptor, complement component (3d/Epstein Barr virus) receptor 2, Complement receptor type 2, Cr2, EBV receptor, Epstein-Barr virus receptor

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesC3DR, CD21, CR, CR2, CVID7, SLEB9
Gene ID(Human) 1380
Gene symbolCR2
UniProt ID(Human) P20023
Human CD21/CR2/EBV receptor quantitates human CD21/CR2/EBV receptor in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CD21/CR2/EBV receptor.人CD21 / CR2 / EBV受体定量检测血清,血浆,上清液中的人CD21 / CR2 / EBV受体。该检测试剂盒将专门识别天然和重组人CD21 / CR2 / EBV受体。Target information 靶标信息CD21 (complement receptor 2, CR2, C3D receptor, EBV receptor) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to follicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands. CD21 functions as receptor for C3d, C3dg and iC3b complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation. Genetic variations in the CD21 gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively, spliced transcript variants encoding different isoforms of CD21 have been found.CD21(补体受体2,CR2,C3D受体,EBV受体)结合C3补体片段,尤其是其分解片段,这些片段共价结合在补体激活表面或抗原上。 CD21在免疫复合物的摄取和保留,记忆B细胞的存活以及对T依赖性抗原的体液反应的形成和维持中具有重要作用。 CD21也是Epstein-Barr病毒结合的关键受体,并参与peripheral病毒靶向卵泡树突状细胞并在外周暴露于病毒后加速神经侵袭。 CD21(sCD21)的可溶形式从淋巴细胞表面脱落,并保持其结合各自配体的能力。 CD21充当C3d,C3dg和iC3b补体成分,EBV和IFNalpha的受体。 CD21与CD23结合,并与CD19,CD81和Leu13结合,形成参与B细胞活化的大信号转导复合物。 CD21基因的遗传变异与系统性红斑狼疮9型(SLEB9)的易感性有关。或者,已经发现了编码不同CD21同工型的剪接转录变体。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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