Human GFR alpha-1/GDNF R ELISA Kit ELISA试剂盒,Human GFR alpha-1/GDNF R ELISA Kit/人GFR alpha-1 / GDNF R ELISA试剂盒

2024-10-24

Human GFR alpha-1/GDNF R ELISA Kit/人GFR alpha-1 / GDNF R ELISA试剂盒

货号:EH217RB,EH217RBX5,EH217RBX10

规格:96 Tests,5X96 Tests,10X96 tests

价格:6327,28472,54564

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.35 ng/mL

检测范围0.35-80 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameGFR alpha-1
Protein aliasesGDNF family receptor alpha-1, GDNF receptor alpha-1, GDNFR-alpha-1, Glial cell line-derived neurotrophic factor receptor alpha, GPI-linked anchor protein, PI-linked cell-surface accessory protein, RET ligand 1, TGF-beta-related neurotrophic factor receptor 1

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesGDNFR, GDNFRA, GFR-ALPHA-1, GFRA1, RET1L, RETL1, TRNR1
Gene ID(Human) 2674
Gene symbolGFRA1
UniProt ID(Human) P56159
Human GFR alpha-1/GDNF R quantitates human GFR alpha-1/GDNF R in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human GFR alpha-1/GDNF R.人GFR alpha-1 / GDNF R定量测定血清,血浆,上清液中的人GFR alpha-1 / GDNFR。 该检测试剂盒将专门识别天然和重组人GFR alpha-1 / GDNFR。Target information 靶标信息Glial cell line-derived neurotrophic factor (GDNF) is a potent survival factor for central and peripheral neurons and is essential for the development of kidneys and the enteric nerves system. Physiological responses to GDNF require the presence of a novel glycosylphosphadidylinositol linked protein GDNFRalpha, which is a cell surface receptor for GDNF. The cDNAs encoding GDNFRalpha from human, rat, chicken and mouse have been cloned recently. GDNFRalpha was also termed Ret ligand 1 (RETL1) or TGF-beta-related neurotrophic factor receptor 1 (TrnR1) and nominated as GFR-a-1 recently. GFR-a-1 binds GDNF specifically and mediates activation of the Ret protein tyrosine kinase (PTK). Thus, GDNF, GFR-a and the Ret PTK form a complex to transduce GDNF signal and to mediate GDNF function.胶质细胞源性神经营养因子(GDNF)是中枢神经和外周神经元的有效存活因子,对肾脏和肠神经系统的发育至关重要。 对GDNF的生理反应需要存在一种新的糖基磷酸二甘油肌醇连接蛋白GDNFRalpha,它是GDNF的细胞表面受体。 最近已经克隆了来自人,大鼠,鸡和小鼠的编码GDNFRalpha的cDNA。 GDNFRalpha也被称为Ret配体1(RETL1)或TGF-beta相关的神经营养因子受体1(TrnR1),最近被命名为GFR-a-1。 GFR-a-1特异性结合GDNF并介导Ret蛋白酪氨酸激酶(PTK)的激活。 因此,GDNF,GFR-α和Ret PTK形成复合物以转导GDNF信号并介导GDNF功能。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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