Human IL-7 R alpha/CD127 ELISA Kit ELISA试剂盒,Human IL-7 R alpha/CD127 ELISA Kit/人IL-7 R alpha / CD127 ELISA试剂盒

2024-10-24

Human IL-7 R alpha/CD127 ELISA Kit/人IL-7 R alpha / CD127 ELISA试剂盒

货号:EH276RB,EH276RBX5,EH276RBX10

规格:96 Tests,5X96 Tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.14 ng/mL

检测范围0.14-100 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameCD127
Protein aliasesCD127, CD127 antigen, CDw127, IL-7 receptor subunit alpha, IL-7R subunit alpha, interleukin 7 receptor alpha chain, interleukin 7 receptor isoform H5-6, Interleukin-7 receptor subunit alpha

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesCD127, CDW127, IL-7R-alpha, IL7R, IL7RA, ILRA
Gene ID(Human) 3575
Gene symbolIL7R
UniProt ID(Human) P16871
Human IL-7 R alpha/CD127 quantitates human IL-7 R alpha/CD127 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human IL-7 R alpha/CD127.人IL-7 R alpha / CD127定量检测血清,血浆,上清液中的人IL-7 R alpha / CD127。该检测试剂盒将只识别天然和重组人IL-7 R alpha / CD127。Target information 靶标信息CD127 (Interleukin-7, IL-7) is a glycoprotein involved in the regulation of lymphopoiesis. The response of cells to CD127 is dependent on the presence of the interleukin 7 receptor (IL7R); the active receptor is an alpha/gamma chain heterodimer. CD127 consists of an alpha chain and a gamma chain. The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules. CD127 promotes the proliferation of precursor B cells, thymocytes, T cell progenitors, and mature CD4+ and CD8+ T cells. The biological effects of IL7 are mediated by the binding of IL7 to the specific cell surface receptor. Diseases associated with CD127 dysfunction include severe combined immunodeficiency and T cell negative/B cell negative/NK positive severe combined immunodeficiency.CD127(白介素7,IL-7)是一种糖蛋白,参与淋巴细胞生成的调节。细胞对CD127的反应取决于白介素7受体(IL7R)的存在。活性受体是α/γ链异二聚体。 CD127由一条α链和一条γ链组成。 γ(c)链也与白介素2受体相关,主要用于激活IL7R复合物的信号转导,而IL7R的α链则通过与细胞质信号分子的结合来确定特定的信号事件。 CD127促进前体B细胞,胸腺细胞,T细胞祖细胞以及成熟的CD4 +和CD8 + T细胞的增殖。 IL7的生物学效应是由IL7与特定细胞表面受体的结合介导的。与CD127功能障碍相关的疾病包括严重的合并免疫缺陷和T细胞阴性/ B细胞阴性/ NK阳性严重合并免疫缺陷。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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