Human Integrin alpha-M/CD11b/MAC-1 ELISA Kit ELISA试剂盒,Human Integrin alpha-M/CD11b/MAC-1 ELISA Kit/人整合素alpha-M / CD11b / MAC-1-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Human Integrin alpha-M/CD11b/MAC-1 ELISA Kit ELISA试剂盒,Human Integrin alpha-M/CD11b/MAC-1 ELISA Kit/人整合素alpha-M / CD11b / MAC-1

2024-10-24

Human Integrin alpha-M/CD11b/MAC-1 ELISA Kit/人整合素alpha-M / CD11b / MAC-1 ELISA试剂盒

货号：EH279RB,EH279RBX5,EH279RBX10

规格：96 Tests,5X96 Tests,10X96 tests

价格：6641,29884,57271

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：人

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	2.5 ng/mL
检测范围	2.5-600 ng/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	CD11b
Protein aliases	antigen CD11b (p170), CD11 antigen-like family member B, CD11b, Cell surface glycoprotein MAC-1 subunit alpha, complement component 3 receptor 3 subunit, CR-3 alpha chain, Integrin alpha-M, integrin, alpha M (complement component 3 receptor 3 subunit), Leukocyte adhesion receptor MO1, macrophage antigen alpha polypeptide, Neutrophil adherence receptor, neutrophil adherence receptor alpha-M subunit
物种（Tested）	人
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	CD11B, CR3A, ITGAM, MAC-1, MAC1A, MO1A, SLEB6
Gene ID	(Human) 3684
Gene symbol	ITGAM
UniProt ID	(Human) P11215

Human Integrin alpha-M/CD11b/MAC-1 quantitates human Integrin alpha-M/CD11b/MAC-1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Integrin alpha-M/CD11b/MAC-1.人整联蛋白α-M/ CD11b / MAC-1定量测定血清，血浆，上清液中的人整联蛋白α-M/ CD11b / MAC-1。该检测试剂盒将专门识别天然和重组人整联蛋白α-M/ CD11b / MAC-1。Target information 靶标信息CD11b (integrin alpha-M, ITGAM, integrin alpha-X, ITGAX) is a 165 kDa adhesion molecule that associates non-covalently with integrin beta-2 (CD18). The CD11b/CD18 heterodimeric complex is also known as integrin alpha-M beta-2, Mac-1, and CR3 (complement receptor 3). CD11b is expressed on the surface of monocytes/macrophages, granulocytes, activated lymphocytes, a subset of NK cells, a subset of dendritic cells, and microglia in the brain. CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X -these adhesions are critical for cell-cell and cell-matrix interactions. CD11b is expressed on 8% of spleen cells, 44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Further, peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Diseases associated with CD11b dysfunction include systemic lupus erythematosus 6 and ITGAM-related susceptibility to systemic lupus erythematosus.CD11b（整合素α-M，ITGAM，整合素α-X，ITGAX）是一个165 kDa的粘附分子，与整合素beta-2（CD18）非共价结合。 CD11b / CD18异二聚体复合物也称为整联蛋白α-Mbeta-2，Mac-1和CR3（补体受体3）。 CD11b在脑中的单核细胞/巨噬细胞，粒细胞，活化的淋巴细胞，NK细胞的一部分，树突状细胞的一部分和小胶质细胞的表面表达。 CD11b / CD18充当ICAM-1（CD54），ICAM-2（CD102），ICAM-4（CD242），CD14，CD50，CD23，肝素，iC3b，纤维蛋白原和X因子的受体-这些黏附对于细胞-细胞和细胞-基质相互作用。 CD11b在8％的脾细胞，44％的骨髓细胞和不到1％的胸腺细胞上表达，通常在神经组织中用作小胶质细胞标记物。 CD11b的表达在单核细胞成熟期间增加，并且表达水平在组织巨噬细胞上有所不同。此外，据报道腹膜巨噬细胞比脾巨噬细胞表达更高水平的CD11b。与CD11b功能障碍相关的疾病包括系统性红斑狼疮6和ITGAM相关的系统性红斑狼疮易感性。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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Human Integrin alpha-M/CD11b/MAC-1 ELISA Kit ELISA试剂盒,Human Integrin alpha-M/CD11b/MAC-1 ELISA Kit/人整合素alpha-M / CD11b / MAC-1

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