Human Importin alpha 2/KPNA2/SRP1-alpha ELISA Kit,Human Importin alpha 2/KPNA2/SRP1-alpha ELISA Kit/人Importin alpha 2 / KPNA2 /

2024-10-24

Human Importin alpha 2/KPNA2/SRP1-alpha ELISA Kit/人Importin alpha 2 / KPNA2 / SRP1-alpha ELISA试剂盒

货号:EH278RB,EH278RBX5,EH278RBX10

规格:96 Tests,5X96 Tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

2 ng/mL

检测范围2-500 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameKPNA2
Protein aliasesImportin subunit alpha-1, importin subunit alpha-2, importin-alpha-P1, karyopherin alpha 2 (RAG cohort 1, importin alpha 1), Karyopherin subunit alpha-2, pendulin, RAG cohort protein 1, SRP1-alpha

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesIPOA1, KPNA2, QIP2, RCH1, SRP1, SRP1-alpha, SRP1alpha
Gene ID(Human) 3838
Gene symbolKPNA2
UniProt ID(Human) P52292
Human Importin alpha 2/KPNA2/SRP1-alpha quantitates human Importin alpha 2/KPNA2/SRP1-alpha in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Importin alpha 2/KPNA2/SRP1-alpha.人Importin alpha 2 / KPNA2 / SRP1-alpha定量检测血清,血浆,上清液中的人Importin alpha 2 / KPNA2 / SRP1-alpha。该检测试剂盒将专门识别天然和重组人Importin alpha 2 / KPNA2 / SRP1-alpha。Target information 靶标信息The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1, which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in VJ recombination.蛋白质进入细胞核的过程至少涉及两个步骤。第一个是蛋白质的能量非依赖性对接,第二个是通过核孔复合体的能量依赖性易位。导入的蛋白质需要一个核定位序列,该序列通常由一个碱性氨基酸的短区域或两个这样的大约相隔10个氨基酸的区域组成。已经在不同系统中鉴定了参与核导入第一步的蛋白质。其中包括非洲爪蟾蛋白importin及其酵母同源物SRP1,它们与NLS结合。 KPNA2蛋白与DNA解旋酶Q1和SV40 T抗原的NLS相互作用,并可能参与蛋白的核转运。 KPNA2也可能在VJ重组中起作用。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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