NSD2 Monoclonal Antibody (CL1063)

货号：MA5-24621

规格：100 µL

价格：5548

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Recombinant protein corresponding to Human NSD2

物种：人

宿主：小鼠

抗体亚型：IgG2b, kappa

克隆号：CL1063

荧光染料：其它

类型:	一抗	同型对照：
浓度：	1 mg/mL	用法：	2-10 µg/mL(ICC) ;2-10 µg/mL(IF);1:500-1:1,000(IHC);1:500-1:1,000(WB)

产品详细信息Immunogen sequence: SANGKTPSCE VNRECSVFLS KAQLSSSLQE GVMQKFNGHD ALPFIPADKL KDLTSRVFNG EPGAHDAKLR FESQEMKGIG TPPNTTPIKN GSPEIKLKIT KTYMNGKPLF ESSICGDHighest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.Binds to an epitope located within the peptide sequence ALPFIPADKL as determined by overlapping synthetic peptides. 靶标信息This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.

数据：

NSD2 Antibody (MA5-24621) in ICCImmunocytochemistry-Immunofluorescence analysis of NSD2 in U-251 cells using NSD2 Monoclonal Antibody (CL1063) (Product # MA5-24621), showing specific staining in the nucleoplasm in green. Microtubule- and nuclear probes are visualized in red and blue, respectively (where available) NSD2 Antibody (MA5-24621) in IHC Immunohistochemical staining of NSD2 in human duodenum tissue shows strong nuclear immunoreactivity in glandular cells. Samples were probed using a NSD2 Monoclonal Antibody (Product # MA5-24621).

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