Rat bFGF ELISA Kit ELISA试剂盒,Rat bFGF ELISA Kit/大鼠bFGF ELISA试剂盒

2024-10-24

Rat bFGF ELISA Kit/大鼠bFGF ELISA试剂盒

货号:ERA4RB,ERA4RBX5

规格:96 Tests,5X96 Tests

价格:6641,29884

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:大鼠

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

2 pg/mL

检测范围2-500 pg/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameFGF2
Protein aliasesBasic fibroblast growth factor, bFGF, FGF-2, Fibroblast growth factor 2, HBGF-2, Heparin-binding growth factor 2

物种(Tested)

大鼠

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesbFGF, Fgf-2, Fgf2
Gene ID(Rat) 54250
Gene symbolFgf2
UniProt ID(Rat) P13109
Rat bFGF quantitates rat bFGF in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat bFGF.大鼠bFGF可定量测定血清,血浆,上清液中的大鼠bFGF。该检测试剂盒将专门识别天然和重组大鼠bFGF。Target information 靶标信息FGF2 (FGFb, fibroblast growth factor basic) belongs to the fibroblast growth factor (FGF) family, and interacts with high-affinity transmembrane receptors to influence cell proliferation and tissue neovascularization. FGF2 exists as five isoforms with distinct intracellular localizations and functions. The 18 kDa isoform is predominantly cytosolic and acts through cell surface receptors, whereas the 22, 22.5, 24 and 34 kDa isoforms are nuclear and may signal independent of transmembrane receptor pathways. In humans, the gene is located on the q arm of chromosome 4. FGF2 has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for FGF2 contains multiple polyadenylation sites, and is alternatively translated from non-AUG and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. Diseases associated with FGF2 dysfunction include Kaposi Sarcoma and corneal neovascularization.FGF2(FGFb,碱性成纤维细胞生长因子)属于成纤维细胞生长因子(FGF)家族,与高亲和性跨膜受体相互作用,影响细胞增殖和组织新血管形成。 FGF2以具有不同细胞内定位和功能的五种同工型形式存在。 18 kDa的同工型主要是胞质的,并通过细胞表面受体起作用,而22、22.5、24和34 kDa的同工型是有核的,并且可能独立于跨膜受体途径发出信号。在人类中,该基因位于4号染色体的q臂上。FGF2与多种生物学过程有关,例如肢体和神经系统发育,伤口愈合和肿瘤生长。 FGF2的mRNA包含多个聚腺苷酸化位点,并且可以从非AUG和AUG起始密码子进行翻译,从而产生具有不同特性的五个不同同工型。 CUG起始的同工型位于细胞核中,负责内分泌作用,而AUG起始的形式主要是胞质的,并负责该FGF的旁分泌和自分泌作用。与FGF2功能障碍相关的疾病包括卡波济肉瘤和角膜新生血管。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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