Rat MMP-2 ELISA Kit ELISA试剂盒,Rat MMP-2 ELISA Kit/大鼠MMP-2 ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rat MMP-2 ELISA Kit ELISA试剂盒,Rat MMP-2 ELISA Kit/大鼠MMP-2 ELISA试剂盒

2024-10-24

Rat MMP-2 ELISA Kit/大鼠MMP-2 ELISA试剂盒

货号：ERA42RB,ERA42RBX5

规格：96 Tests,5X96 Tests

价格：6641,29884

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：大鼠

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	0.6 ng/mL
检测范围	0.614-150 ng/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	MMP2
Protein aliases	72 kDa gelatinase, 72 kDa type IV collagenase, Gelatinase A, matrix metalloproteinase 2, Matrix metalloproteinase-2, MMP-2, PEX
物种（Tested）	大鼠
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	Mmp2
Gene ID	(Rat) 81686
Gene symbol	Mmp2
UniProt ID	(Rat) P33436

Rat MMP-2 quantitates rat MMP-2 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat MMP-2.大鼠MMP-2定量测定血清，血浆，上清液中的大鼠MMP-2。该检测试剂盒将专门识别天然和重组大鼠MMP-2。Target information 靶标信息MMP (matrix metalloproteinase) are proteolytic enzymes capable of degrading connective tissue components. MMP have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs). MMPa and TIMPs play a significant role in regulating angiogenesis. MMP2 is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids, and contains the basic structure of propeptide, catalytic, and hemopexin domains. The matrix metalloproteinases (MMPs) are a family of at least eighteen secreted and membrane-bound zincendopeptidases. Collectively, these enzymes can degrade all the components of the extracellular matrix, including fibrillar and non-fibrillar collagens, fibronectin, laminin and basement membrane glycoproteins. In general, a signal peptide, a propeptide, and a catalytic domain containing the highly conserved zinc-binding site characterizes the structure of the MMPs. Functionally, MMP2 is involved in tissue remodeling. Mutations in MMP-2 gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms of MMP-2 have been found.MMP（基质金属蛋白酶）是能够降解结缔组织成分的蛋白水解酶。 MMP具有常见的激活方式，假定的金属结合活性位点区域中的保守氨基酸序列，并被金属蛋白酶（TIMP）的特定组织抑制剂所抑制。 MMPa和TIMP在调节血管生成中起重要作用。 MMP2合成为一种631个氨基酸的酶，该酶通过切割前80个氨基酸而被激活，并包含前肽，催化和血红素结构域的基本结构。基质金属蛋白酶（MMP）是至少十八种分泌的和膜结合的锌内肽酶的家族。这些酶可以共同降解细胞外基质的所有成分，包括纤维状和非纤维状胶原，纤连蛋白，层粘连蛋白和基底膜糖蛋白。通常，包含高度保守的锌结合位点的信号肽，前肽和催化结构域表征了MMP的结构。在功能上，MMP2参与组织重塑。 MMP-2基因的突变与Winchester综合征和结节性关节炎-骨溶解症（NAO）综合征有关。已经发现了编码MMP-2不同同工型的两个转录物变体。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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Rat MMP-2 ELISA Kit ELISA试剂盒,Rat MMP-2 ELISA Kit/大鼠MMP-2 ELISA试剂盒

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