SIRT2 Polyclonal Antibody

货号：PA1-25472

规格：100 µL

价格：4880

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Synthetic peptide corresponding to the C-terminal

物种：人/小鼠

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	一抗	同型对照：
浓度：	1.1 mg/mL	用法：	1:50(ICC);1:50(IF);1:2000(WB)

产品详细信息Recommended positive controls: NIH3T3.Predicted molucular weight of 43 kDa.靶标信息The SIRT2 protein (also known as Sirtuin for Silent Mating Type Information 2-Homolog) is a NAD-dependent deacytylase (NDAC) that has been shown to control gene silencing, cell cycle, and DNA damage repair. It is believed that SIRT2 may act as a tumor suppressor in human gliomas and may also serve as a novel molecular marker for these cells. SIRT2 has also been shown to act as a redox sensor to help regulate muscle gene expression in response to food intake and exercise. SIRT2 acts in the phosphorylation cascade involving mitosis where SIRT2 is phosphorylated in late G2 phase, during M phase, and into cytokinesis.

数据：

SIRT2 Antibody (PA1-25472) in ICCImmunocytochemistry-Immunofluorescence analysis of SIRT2 in NIH3T3 cells using SIRT2 Polyclonal Antibody (Product # PA1-25472) at 20 µg/mL (green) with DAPI (blue). SIRT2 Antibody (PA1-25472) in WBWestern Blot analysis of SIRT2 was performed by loading NIH3T3 cell lysates. Proteins were transferred to a membrane and probed with a SIRT2 Polyclonal Antibody (Product # PA1-25472) at dilutions of Lane 1 : Antibody 0.25 µg/mL, Lane 2 : Antibody 0.5 µg/mL, Lane 3 : Negative control: without first antibody.

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