Porcine TNF-alpha ELISA Kit ELISA试剂盒,Porcine TNF-alpha ELISA Kit/猪TNF-alpha ELISA试剂盒

2024-10-24

Porcine TNF-alpha ELISA Kit/猪TNF-alpha ELISA试剂盒

货号:ES24RB,ES24RBX5

规格:96 Tests,5X96 Tests

价格:6327,28472

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:其它

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

20 pg/mL

检测范围20-10 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameTNF alpha
Protein aliasesC-domain 1, C-domain 2, Cachectin, ICD1, ICD2, Intracellular domain 1, Intracellular domain 2, N-terminal fragment, NTF, TNF-a, TNF-alpha, Tumor necrosis factor, tumor necrosis factor (TNF superfamily, member 2), tumor necrosis factor alpha, tumor necrosis factor alpha precursor, Tumor necrosis factor ligand superfamily member 2, membrane form, soluble form

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesTNF, TNFA, TNFSF2
Gene ID(Pig) 397086
Gene symbolTNF
Porcine TNF-alpha quantitates porcine TNF-alpha in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant porcine TNF-alpha.猪TNF-α定量测定血清,血浆,上清液中的猪TNF-α。该检测试剂盒将专门识别天然和重组猪TNF-α。Target information 靶标信息TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophage and bind to its receptors, TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. TNF alpha is involved in the regulation of immune cells, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS-PAGE under non-reducing conditions. Knockout studies in mice also suggested the neuroprotective function of TNF alpha, and has been observed to causes tumor necrosis when injected into tumor-bearing mice. Other functions of TNF-alpha include its role in the immune response to bacterial, viral, parasitic and certain fungal infections, as well as its role in the necrosis of specific tumors. TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon-gamma in its cytotoxicity. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.TNFα是一种多功能促炎细胞因子,属于肿瘤坏死因子(TNF)超家族。该细胞因子主要由巨噬细胞分泌,并与其受体TNFRSF1A / TNFR1和TNFRSF1B / TNFBR结合。 TNFα参与免疫细胞的调节,细胞增殖,分化,凋亡,脂质代谢和凝血。 TNFα以两个,三个或五个非共价连接的单元的多聚体形式存在,但在非还原条件下SDS-PAGE后显示一个17 kDa的条带。小鼠的基因敲除研究还提示了TNFα的神经保护功能,并且已经观察到注射入荷瘤小鼠时会引起肿瘤坏死。 TNF-α的其他功能包括其在对细菌,病毒,寄生虫和某些真菌感染的免疫反应中的作用,以及在特定肿瘤坏死中的作用。 TNF-α引起某些转化细胞的细胞溶解或细胞停滞,与干扰素-γ的细胞毒性具有协同作用。该细胞因子与多种疾病有关,包括自身免疫性疾病,胰岛素抵抗和癌症。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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