Equine IL-1alpha ELISA Kit ELISA试剂盒,Equine IL-1alpha ELISA Kit/马IL-1 alpha ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Equine IL-1alpha ELISA Kit ELISA试剂盒,Equine IL-1alpha ELISA Kit/马IL-1 alpha ELISA试剂盒

2024-10-24

Equine IL-1alpha ELISA Kit/马IL-1 alpha ELISA试剂盒

货号：EE2RB,EE2RBX5,EE2RBX10

规格：96 Tests,5X96 Tests,10X96 tests

价格：6641,29884,57271

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：其它

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	0.82 pg/mL
检测范围	0.82-200 pg/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	IL-1 alpha
Protein aliases	IL-1 alpha, Interleukin-1 alpha
物种（Tested）	马
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	IL1A
Gene ID	(Horse) 100064969
UniProt ID	(Horse) Q28385
Gene symbol	IL1A

Equine IL-1alpha quantitates equine IL-1alpha in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant equine IL-1alpha.马IL-1α定量测定血清，血浆，上清液中的马IL-1α。该检测试剂盒将只识别天然和重组马IL-1α。Target information 靶标信息IL-1 alpha (Interleukin-1 alpha) is a proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 alpha is coded by the IL1A gene and signals through two receptors, IL-1RI and IL-1RII, both of which are shared with IL-1 beta. IL1A is located on the q arm on chromosome 2 at position 13. IL-1 alpha plays an important role in innate host defense by triggering the production of other proinflammatory cytokines in target cells and initiating acute-phase responses. IL-1 alpha activity can be moderated by IL-1 Receptor Antagonist (IL-1RA), a protein produced by many cell types that blocks receptor binding through competitive inhibition. IL-1 alpha is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. Further, IL-1 alpha is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury and induces apoptosis. The IL1A gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. IL1 alpha regulates the activities of NF-kappaB and mitogen-activated protein kinases. IL-1 alpha can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-1 alpha are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.IL-1 alpha（白介素-1 alpha）是单核细胞，巨噬细胞和树突状细胞表达的促炎细胞因子。 IL-1 alpha由IL1A基因编码，并通过两个受体IL-1RI和IL-1RII发出信号，这两个受体均与IL-1 beta共享。 IL1A位于2号染色体第13位的q臂上。IL-1alpha通过触发靶细胞中其他促炎细胞因子的产生并启动急性期反应，在先天宿主防御中发挥重要作用。 IL-1受体拮抗剂（IL-1RA）可以调节IL-1α的活性，IL-1RA是许多细胞类型产生的一种蛋白质，通过竞争性抑制作用阻断受体结合。 IL-1α是参与多种免疫反应，炎症过程和造血作用的多效细胞因子。此外，IL-1α由单核细胞和巨噬细胞产生为前蛋白，其被蛋白水解处理并响应细胞损伤而释放并诱导凋亡。 IL1A基因和其他8个白介素1家族基因在2号染色体上形成一个细胞因子基因簇。IL1α调节NF-κB和有丝分裂原激活的蛋白激酶的活性。 IL-1α可以刺激IL6和环氧合酶2（PTGS2 / COX-2）的表达，并增强一氧化氮（NO）的产生。高水平的IL-1α与几种慢性炎症性疾病有关，包括类风湿关节炎，牛皮癣和多发性硬化症。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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Equine IL-1alpha ELISA Kit ELISA试剂盒,Equine IL-1alpha ELISA Kit/马IL-1 alpha ELISA试剂盒

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