ING3 Polyclonal Antibody

货号：PA5-109857

规格：100 µL

价格：4711

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Recombinant fusion protein containing a sequence c

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	一抗	同型对照：
浓度：	3.99mg/mL	用法：	1:50-1:200（ICC）；1:500-1:2000(WB）

产品详细信息Sequence of this protein is as follows: MLYLEDYLEM IEQLPMDLRD RFTEMREMDL QVQNAMDQLE QRVSEFFMNA KKNKPEWREE QMASIKKDYY KALEDADEKV QLANQIYDLQ HF靶标信息The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.

数据：

ING3 Antibody (PA5-109857) in ICCImmunocytochemistry analysis of ING3 in A549 cells. Samples were incubated in polyclonal ING3 antibody (Product # PA5-109857) using a dilution of 1:100, followed by DAPI. ING3 Antibody (PA5-109857) in WBWestern blot analysis of ING3 in 293T, SW620, HeLa, rat testis. Samples were incubated in polyclonal ING3 antibody (Product # PA5-109857) using a dilution of 1:1000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10000.

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技术参数

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