Mouse BID ELISA Kit ELISA试剂盒,Mouse BID ELISA Kit/小鼠BID ELISA试剂盒

2024-10-24

Mouse BID ELISA Kit/小鼠BID ELISA试剂盒

货号:EM10RB,EM10RBX5,EM10RBX10

规格:96 Tests,5X96 Tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:小鼠

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.41 ng/mL

检测范围0.41-100 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameBID
Protein aliasesBH3-interacting domain death agonist, BH3-interacting domain death agonist p11, BH3-interacting domain death agonist p13, BH3-interacting domain death agonist p15, BID, p11 BID, p13 BID, p15 BID, p22 BID

物种(Tested)

小鼠

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliases2700049M22Rik, AI875481, AU022477, Bid
Gene ID(Mouse) 12122
Gene symbolBid
UniProt ID(Mouse) P70444
Mouse BID quantitates mouse BID in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse BID.小鼠BID定量测定血清,血浆,上清液中的小鼠BID。该检测试剂盒将专门识别天然和重组小鼠BID。Target information 靶标信息BID is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. Bid is a member of the BCL-2 family of cell death regulators. BID is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. BID is also a pro-apoptotic member of the Bcl 2 family. BID usually exists in an inactive form in the cytosolic fraction of living cells and becomes cleaved and activated by caspase 8 in response to TNF alpha or Fas ligand. Once BID is cleaved, the C-terminal 15 kDa fragment of BID (p15) translocates onto mitochondria and is sufficient to trigger cytochrome c release, resulting in cell apoptosis. BID serves as a direct molecular link between caspase 8 activation and mitochondrial death machinery.BID是与激动剂BAX或拮抗剂BCL2异源二聚体的死亡激动剂。 Bid是BCL-2细胞死亡调节剂家族的成员。 BID是由caspase-8(CASP8)诱导的线粒体损伤的介体; CASP8切割该编码的蛋白质,并且COOH末端部分易位至线粒体,从而触发细胞色素c的释放。 BID也是Bcl 2家族的促凋亡成员。 BID通常以无活性形式存在于活细胞的胞质中,并响应TNFα或Fas配体而被caspase 8裂解并激活。切割BID后,BID的C端15 kDa片段(p15)易位到线粒体上,足以触发细胞色素c释放,导致细胞凋亡。 BID充当caspase 8激活与线粒体死亡机制之间的直接分子链接。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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