EED Polyclonal Antibody

货号：PA5-84480

规格：100 µL

价格：6049

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Recombinant protein corresponding to Human EED

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	一抗	同型对照：
浓度：	0.1 mg/mL	用法：	1:50-1:200（IHC(P)）；0.04-0.4 µg/mL(WB）

产品详细信息Immunogen sequence: HPLLAVAGSR GIIRIINPIT MQCIKHYVGH GNAINELKFH PRDPNLLLSV SKDHALRLWN IQTDTLVAIF GGVEGHRDEV LSADYDLLGE KIMSCGMDHS LK靶标信息The EED protein (WAIT-1 or WD protein associated with integrin cytoplasmic tails-1), also called embryonic ectoderm development, is a member of the superfamily of WD-40 repeat proteins and widely conserved polycomb group (PcG) family of proteins. The polycomb group (PcG) is a large and evolutionarily conserved set of genes whose products act in multimeric complexes to modify histones, which are then thought to cause stable and heritable states of transcriptional repression. EED shuttles betweenthe nucleus and the plasma membrane and can interact with the cytoplasmic tail of integrin Beta-7 subunit. EED exerted an antiviral activity at the late stage of HIV-1 replication.

数据：

EED Antibody (PA5-84480) in IHCImmunohistochemical analysis of EED in human testis using a EED polyclonal antibody (Product # PA5-84480). The analysis shows moderate to strong nuclear positivity in cells in seminiferous ducts.

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