Mouse SLAM/CD150 ELISA Kit ELISA试剂盒,Mouse SLAM/CD150 ELISA Kit/小鼠SLAM / CD150 ELISA试剂盒

2024-10-24

Mouse SLAM/CD150 ELISA Kit/小鼠SLAM / CD150 ELISA试剂盒

货号:EM70RB,EM70RBX5,EM70RBX10

规格:96 Tests,5X96 Tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:小鼠

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.06 ng/mL

检测范围0.06-12 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameCD150
Protein aliasesCD150, signaling lymphocyte activation molecule, Signaling lymphocytic activation molecule, SLAM family member 1

物种(Tested)

小鼠

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliases4933415F16, AA177906, CD150, CDw150, ESTM51, IPO-3, Slam, Slamf1
Gene ID(Mouse) 27218
Gene symbolSlamf1
UniProt ID(Mouse) Q9QUM4
Mouse SLAM/CD150 quantitates mouse SLAM/CD150 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse SLAM/CD150.小鼠SLAM / CD150定量分析血清,血浆,上清液中的小鼠SLAM / CD150。该检测试剂盒将专门识别天然和重组小鼠SLAM / CD150。Target information 靶标信息CD150 (SLAM, Signaling Lymphocyte Activation Molecule) belongs to the immunoglobulin gene superfamily, and is involved in T cell stimulation. SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation. Activated B cells express the membrane bound form, the soluble form and the cytoplasmic isoforms of SLAM. It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interactions enhances the expansion and differentiation of activated B cells. Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells. Moreover, CD150 is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations CD150 gene may be associated with X-linked lympho-proliferative disease (XLP).CD150(SLAM,信号淋巴细胞激活分子)属于免疫球蛋白基因超家族,参与T细胞刺激。 SLAM在外周血记忆T细胞,T细胞克隆,未成熟胸腺细胞和一定比例的B细胞上组成性表达,并在激活后迅速在幼稚T细胞上诱导。活化的B细胞表达SLAM的膜结合形式,可溶形式和细胞质同工型。提示在B到B和B到T细胞相互作用期间通过同源SLAM-SLAM结合的信号传导增强了活化的B细胞的扩增和分化。报告表明,CD150的胞外域是麻疹病毒的受体,并在T细胞和B细胞上起共激活剂的作用。此外,认为CD150通过其胞质结构域与SH2D1A和PTPN11相互作用。 CD150基因突变可能与X连锁淋巴增生性疾病(XLP)相关。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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