CD326 (EpCAM) Monoclonal Antibody (1B7), Alexa Fluor 700 Thermo ,CD326 (EpCAM) Monoclonal Antibody (1B7), Alexa Fluor 700-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

CD326 (EpCAM) Monoclonal Antibody (1B7), Alexa Fluor 700 Thermo ,CD326 (EpCAM) Monoclonal Antibody (1B7), Alexa Fluor 700

2024-10-24

CD326 (EpCAM) Monoclonal Antibody (1B7), Alexa Fluor 700

货号：56-9326-41,56-9326-42

规格：25 Tests,100Tests

价格：1217,2634

产品类型：流式抗体

品牌：Thermo Fisher

物种：人

宿主：小鼠

抗体亚型：IgG1, kappa

荧光染料：Alexa Fluor 700

抗体类型	单抗	同型对照：	Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), Alexa Fluor 700
浓度：	5 µL/Test	用法：	5 µL (0.25 µg)/test(Flow)
产品详细信息Description: EpCAM (Epithelial cell adhesion molecule, CD326, KSA, TROP1) is a 40 kD cell-surface adhesion molecule participating in homophilic, calcium-independent cell-cell interactions. EpCAM is a type-I transmembrane protein, and is expressed primarily on the basolateral surface of most epithelia. Although normal epithelia express low levels of EpCAM, increased expression has been correlated with increased proliferation and progression to a mesenchymal phenotype. EpCAM has also been used asa diagnostic marker on circulating metastatic carcinoma cells, while cancer cells of non-epithelial origin do not express EpCAM.Applications Reported: This 1B7 antibody has been reported for use in flow cytometric analysis.Applications Tested: This 1B7 antibody has been pre-diluted and tested by flow cytometric analysis of A549 cells. This may be used at 5 µL (0.25 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Alexa Fluor 700 emits at 723 nm and can be excited with the red laser (633-647 nm). Most instruments will require a 685 LP mirror and 710/20 band pass filter. Please make sure that your instrument is capable of detecting this fluorochrome.Excitation: 633-647 nm; Emission: 723 nm; Laser: Red Laser靶标信息Ep-CAM (epithelial adhesion molecule, epithelial specific antigen, ESA) is a transmembrane glycoprotein expressed in the epithelium with a molecular weight of approximately 40 kDa, which functions as an epithelial cell adhesion molecule. Ep-CAM functions as a homotypic calcium-independent cell adhesion molecule, and has a direct impact on cell cycle, proliferation and metabolism of epithelial cells and fibroblasts due to its ability to rapidly induce the proto-oncogene c-myc and the cell cycle regulating genes cyclin A and E. Ep-CAM mediates Ca2+-independent homotypic interactions. Formation of Ep-CAM-mediated adhesions have a negative regulatory effect on adhesions mediated by classic cadherins, which may have strong effects on the differentiation and growth of epithelial cells. Ep-CAM overexpression was suggested to be associated with enhanced epithelial proliferation. Ep-CAM is highly expressed in human carcinomas, and is a marker for tumors of epithelial lineage. Ep-CAM is expressed on baso-lateral cell surface in most simple epithelia and many carcinoma types. Also, Ep-CAM reportedly distinguishes adenocarcinomas from pleural mesotheliomas.
数据
CD326 (EpCAM) Antibody (56-9326-42) in FlowA549 cells were stained with Mouse IgG1 kappa Isotype Control, Alexa Fluor 700 (Product # 56-4714-80) (blue histogram) or CD326 (EpCAM) Monoclonal Antibody, Alexa Fluor 700 (purple histogram). Viable cells were used for analysis, as determined by 7-AAD (Product # 00-6993-50).
推荐产品：
二抗荧光二抗免疫组化一抗标签抗体

技术参数

© bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：https://gibcohyclone.cn/thread-48684.htm

特别声明：以上内容(如有图片亦包括在内)来源于授权厂家或网络，如有侵权，请联系删除，本平台不提供信息存储服务。

Notice: The content above (including the pictures if any)comes from authorized manufacturers or networks. In case of infringement, please contact to delete it. This platform does not provide information storage services.

产品询价需求提交

CD326 (EpCAM) Monoclonal Antibody (1B7), Alexa Fluor 700 Thermo ,CD326 (EpCAM) Monoclonal Antibody (1B7), Alexa Fluor 700

相关推荐