Rabbit anti Human DDX39B antibody 伯乐 DDX39B 抗体 人VPA00378

2024-10-28

Rabbit anti Human DDX39B antibody

货号:VPA00378

规格:100 µl

市场价格:2890

产品类型:免疫组化一抗

品牌:Bio-Rad

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti Human DDX39B antibodyrecognizes DDX39B, also known as DEAD-box helicase 39B, 56 kDa U2AF65-associated protein, UAP56, ATP-dependent RNA helicase p47, HLA-B-associated transcript 1 protein, nuclear RNA helicase (DEAD family) and spliceosome RNA helicase BAT1.The DDX39B gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and it also plays an important role in mRNA export from the nucleus to the cytoplasm. DDX39B belongs to a cluster of genes localized in the vicinity of the genes encoding tumor necrosis factor alpha and tumor necrosis factor beta. These genes are all within the human major histocompatibility complex class III region. Mutations in DDX39B may be associated with rheumatoid arthritis. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on both chromosomes 6 and 11. Read-through transcription also occurs between DDX39B and the upstream ATP6V1G2 (ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2) gene (provided by RefSeq, Feb 2011).Rabbit anti DDX39B antibody detects a band of 49 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationRabbit polyclonal antibody purified by affinity chromatography.
Buffer SolutionPhosphate buffered saline.
Preservative Stabilisers0.09% Sodium Azide (NaN3).
ImmunogenKLH-conjugated synthetic peptide corresponding to aa 351-380 of human DDX39B
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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