Goat anti Human NQO1 antibody 伯乐 NQO1 抗体 人VPA00163

2024-10-28

Goat anti Human NQO1 antibody

货号:VPA00163

规格:100 µl

市场价格:3613

产品类型:免疫组化一抗

品牌:Bio-Rad

物种:人

宿主:山羊

抗体亚型:IgG

荧光染料:Purified

产品介绍
Goat anti Human NQO1 antibodyrecognizes NAD(P)H dehydrogenase [quinone] 1 (NQO1), also known as azoreductase, DT-diaphorase (DTD), menadione reductase, phylloquinone reductase and quinone reductase 1 (QR1).The NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in NQO1 have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized (provided by RefSeq, Jul 2008).Goat anti Human NQO1 antibody detects a band of 29 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationRabbit polyclonal antibody purified by affinity chromatography.
Buffer SolutionTRIS buffered saline.
Preservative Stabilisers0.02% Sodium Azide (NaN3) 0.5% BSA
ImmunogenSynthetic peptide sequence C-SIPTDNQIKARK from the C terminus of NQO1
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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