Goat anti Human PSMB8 antibody 伯乐PSMB8 抗体人 VPA00155-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Goat anti Human PSMB8 antibody 伯乐PSMB8 抗体人 VPA00155

2024-10-28

Goat anti Human PSMB8 antibody

货号： VPA00155

规格：100 µl

市场价格：3613

产品类型：免疫组化一抗

品牌：Bio-Rad

物种：人

宿主：山羊

抗体亚型：IgG

荧光染料：Purified

产品介绍
Goat anti Human PSMB8 antibodyrecognizes proteasome subunit beta type-8, also known as Low molecular mass protein 7, macropain subunit C13, multicatalytic endopeptidase complex subunit C13, proteasome component C13, and proteasome subunit beta-5i.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMB8 encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. PSMB8 is located in the class II region of the MHC (major histocompatibility complex). Expression of PSMB8 is induced by gamma interferon and PSMB8 product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit (provided by RefSeq, Jul 2008).Goat anti Human PSMB8 antibody detects a band of 23 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Goat polyclonal antibody purified by affinity chromatography.
Buffer Solution	TRIS buffered saline.
Preservative Stabilisers	0.02% Sodium Azide (NaN3) 0.5 % BSA
Immunogen	Peptide with the sequence C-DVSDLLHQYREANQ, from the C terminus of the protein sequence
Acknowledgements	PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 WB

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Goat anti Human PSMB8 antibody 伯乐PSMB8 抗体 人 VPA00155

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Goat anti Human PSMB8 antibody 伯乐PSMB8 抗体人 VPA00155