Mouse anti Human PI-3 kinase subunit gamma antibody BIO-RAD VMA00277 Mouse anti Human PI-3 kinase subunit gamma antibody

2024-10-28

Mouse anti Human PI-3 kinase subunit gamma antibody

货号:VMA00277

规格:100μl

市场价格:3205

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:PI-3 kinase subunit gamma

物种:人

宿主:小鼠

抗体亚型:IgG2a

克隆号:OTI6D1

荧光染料:Purified

产品介绍
Mouse anti Human PI-3 kinase subunit gamma antibodyrecognizes the phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, also known as 1-phosphatidylinositol 3-kinase, phosphatidylinositol 3 kinase gamma, p110 gamma, phosphatidylinositol 3-kinase catalytic 110-kD gamma, phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, phosphoinositide-3-kinase gamma catalytic subunit, ptdIns-3-kinase subunit gamma, ptdIns-3-kinase subunit p110-gamma and serine/threonine protein kinase PIK3CG.A product of the PIK3CG gene, PI-3 kinase subunit gamma belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for PIK3CG (provided by RefSeq, Sep 2013).Mouse anti Human PI-3 kinase subunit gamma isoform antibody detects a band of 126 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationMouse monoclonal antibody purified by affinity chromatography from ascites.
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.09% Sodium Azide (NaN3)1% Bovine Serum Albumin50% Glycerol
ImmunogenFull length recombinant human PI-3 kinase subunit gamma (NP_002640) produced in HEK293T cells
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch.
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting1/1000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.Flow CytometryUse 10ul of the suggested working dilution to label 106cells or 100ul human whole blood.
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技术参数

产品应用 wb

产品类型 单克隆抗体

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