Recombinant Human CD120b BIO-RAD PHP215 Recombinant Human CD120b

2024-10-28

Recombinant Human CD120b

货号:PHP215

规格:20 µg

市场价格:3162

产品类型:细胞因子添加物

品牌:Bio-Rad

产品介绍
Recombinant human CD120bis an 18.9 kDa peptide comprised of 174 amino acids representing the soluble form of CD120b. Soluble human CD120b, otherwise known as sTNF receptor type II (sTNFRII), is a member of the tumour necrosis factor receptor (TNFR) superfamily, produced by proteolytic cleavage of the membrane form by the metalloprotease TACE.CD120b plays a key role in regulating the inflammatory response, acting as a receptor for both tumour necrosis factor alpha (TNF-alpha) and TNF-beta, and is also involved in programmed cell death and anti-viral activity. sTNFRII acts as an inhibitor of TNF-alpha induced responses, by acting as a decoy receptor.
产品详情
Target SpeciesHuman
Product FormPurified recombinant protein - lyophilized
PreparationPurified recombinant CD120b expressed inE.coli
ReconstitutionReconstitute with 0.2 ml distilled water. For extended storage the addition of 0.1% BSA is recommended.Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution.
ActivityDetermined by its inhibitory effect of the TNF-alpha mediated cytotoxicity in murine L-929 cells. The ED50for this effect in the presence of 0.25 ng/ml of recombinant human TNF-alpha is 0.125 µg/ml.
Preservative StabilisersNone present
Approx. Protein Concentrations1.0 mg/ml after reconstitution
Protein Molecular Weight18.9 kDa (174 amino acid residues)
Purity>98% by SDS PAGE and HPLC
RegulatoryFor research purposes only
Guarantee3 months from date of reconstitution
存储条件
Prior to reconstitution store at +4℃.After reconstitution store at -20℃.Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application NameVerifiedMin DilutionMax Dilution
Functional Assays
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

技术参数

产品应用 WB;ELISA;FN

产品类型 多克隆抗体

推荐用于 WB;ELISA;FN

© bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪是专业的授权总代理区域代理经销平台。
© 如需询价,请加客服QQ:1749072012 、客服微信:jinshanbio,或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务,数据资源基于CC协议。
© 本文地址:https://gibcohyclone.cn/thread-50654.htm
产品询价需求提交
返回
扫码添加客服微信,咨询产品报价