Recombinant Human BDNF BIO-RAD PHP213 Recombinant Human BDNF

2024-10-28

Recombinant Human BDNF

货号:PHP213

规格:10 µg

市场价格:3247

产品类型:细胞因子添加物

品牌:Bio-Rad

产品介绍
Brain-derived neurotrophic factor (BDNF) is a potent neurotrophin and member of the NGF-beta family, secreted from dense core vesicles, which promotes the growth, differentiation and survival of neurons within, or directly connected to, the central nervous system.BDNF signals through binding to the high affinity receptor trkB, and also binds to the low affinity neurotrophin receptor LNGFR. BDNF is involved in the modulation of short-term synaptic function and in the formation of long-term memory, and reduced levels of BDNF are seen in patients with Alzheimer's and Huntington disease (Girotaet al.2022).
产品详情
Target SpeciesHuman
Product FormPurified recombinant protein - lyophilized
PreparationPurified recombinant BDNF expressed inE.coli
ReconstitutionReconstitute with 100 ul distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution.
ActivityDetermined by its ability to stimulate the proliferation of rat C6 cells. The expected ED50for this effect is 0.5-1.0 μg/ml.
Preservative StabilisersNone present
Approx. Protein Concentrations1.0 mg/ml after reconstitution
Protein Molecular Weight27.0 kDa (119 amino acid homodimer)
Purity>98% by SDS PAGE and HPLC analysis
RegulatoryFor research purposes only
GuaranteeGuaranteed for 3 months from the date of reconstitution or until the date of expiry, whichever comes first. Please see label for expiry date.
存储条件
Prior to reconstitution store at -20℃.After reconstitution store at -20℃.Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application NameVerifiedMin DilutionMax Dilution
Functional Assays
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

技术参数

产品应用 FN

产品类型 重组蛋白

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