Rat anti mouse TREM-1:Alexa Fluor 647 伯乐 Rat anti mouse TREM-1:Alexa Fluor 647-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rat anti mouse TREM-1:Alexa Fluor 647 伯乐 Rat anti mouse TREM-1:Alexa Fluor 647

2024-10-29

Rat anti mouse TREM-1:Alexa Fluor 647

货号：MCA2578A647

规格：100 Tests/1ml

市场价格：3375

产品类型：流式抗体

品牌：Bio-Rad

抗原：TREM-1

物种：小鼠

宿主：大鼠

抗体亚型：IgG2a

克隆号：L5-B8.2A12.3A12c

荧光染料：Alexa Fluor 647

产品介绍
Rat anti Mouse Trem-1 antibody, clone L5-B8.2A12.3A12recognizes mouse triggering receptor expressed on myeloid cells 1 (TREM-1), a 30kD member of the immunoglobulin superfamily expressed on neutrophils and a subset of monocytes. TREM-1 is involved in the microbial inflammatory response. It acts in conjunction with the adaptor protein DAP12 to activate neutrophils and monocytes, leading to the secretion of pro-inflammatory mediators and enhancement of the inflammatory response. Microbial infection also induces the release of soluble form of TREM-1 from monocytes, which is reported to act as an inhibitor of TREM-1.TREM-1 mediates the septic shock pathway, and blocking TREM-1 has been reported to reduce inflammation and increase survival in certain models of bacterial infection.
产品详情
Target Species	Mouse
Product Form	Purified IgG conjugated to Alexa Fluor® 647 - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Fusion Partners	Spleen cells from immunised Balb/c mice were fused with cells of the NS1 myeloma cell line.
Buffer Solution	Phosphate buffered saline
Immunogen	Mouse TREM-1 Fc fusion protein.
Approx. Protein Concentrations	IgG concentration 0.05 mg/ml
Preservative Stabilisers	0.09%Sodium Azide1%Bovine Serum Albumin
Max Ex/Em	Fluorophore	Excitation Max (nm)	Emission Max (nm)
Alexa Fluor®647	650	665
Acknowledgements	This product is provided under an intellectual property licence from Life Technologies Corporation. The transfer of this product is contingent on the buyer using the purchase product solely in research, excluding contract research or any fee for service research, and the buyer must not sell or otherwise transfer this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; (c) manufacturing or quality assurance or quality control, or (d) resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad CA 92008 USA or outlicensing@thermofisher.com
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√	Neat
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
文献
1.Wang, F.et al.(2012) Blocking TREM-1 signaling prolongs survival of mice withPseudomonas aeruginosainduced sepsis.Cell Immunol. 272 (2): 251-8.

技术参数

产品应用 Flow

产品类型单克隆抗体

推荐用于 Flow

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