Rat anti mouse CD88:PE 伯乐 CD88抗体 MCA2457PE-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rat anti mouse CD88:PE 伯乐 CD88抗体 MCA2457PE

2024-10-29

Rat anti mouse CD88:PE

货号：MCA2457PE

规格：100 Tests

市场价格：3162

产品类型：流式抗体

品牌：Bio-Rad

抗原：CD88

物种：小鼠

宿主：大鼠

抗体亚型：IgG2b

克隆号：20/70

荧光染料：PE

产品介绍
Rat anti Mouse CD88 antibody, clone 10/92recognizes murine CD88, a 45 kDa G-protein coupled cell surface receptor, otherwise known as C5aR. The CD88 molecule functions as a receptor for the complement component C5a, a potent proinflammatory molecule and chemoattractant for neutrophils to sites of infection. In mouse, CD88 is expressed on granulocytes, monocytes and macrophages but not on resting or stimulated lymphocytes.Rat anti Mouse CD88 antibody, clone 10/92 does not block the binding of the C5a to murine CD88 (Souriet al.2003).
产品详情
Target Species	Mouse
Product Form	Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilized
Preparation	Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Fusion Partners	Cells from immunised Lou/c were fused with cells of the X63-Ag8.653 myeloma cell line.
Reconstitution	Reconstitute with 1 ml distilled water
Buffer Solution	Phosphate buffered saline
Immunogen	RBL-2H3 transfected cells expressing murine C5aR.
Approx. Protein Concentrations	IgG concentration 0.05 mg/ml
Preservative Stabilisers	0.09%Sodium Azide1%Bovine Serum Albumin
Max Ex/Em	Fluorophore	Excitation Max (nm)	Emission Max (nm)
RPE 488nm laser	496	578
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
Store at +4℃. DO NOT FREEZE.This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√	Neat
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Soruri, A.et al. (2003) Characterization of C5aR expression on murine myeloid and lymphoid cells by the use of a novel monoclonal antibody.Immunol Lett. 88:47-52.2.Shagdarsuren, E.et al.(2010) C5a Receptor Targeting in Neointima Formation After Arterial Injury in Atherosclerosis-Prone Mice.Circulation. 122: 1026-36.3.Manthey, H.D.et al.(2011) Complement C5a inhibition reduces atherosclerosis in ApoE-/- mice.FASEB J. 25: 2447-55.4.Cudaback, E.et al.(2011) Apolipoprotein E isoform-dependent microglia migration.FASEB J. 25: 2082-91.5.Ager, R.R.et al.(2010) Microglial C5aR (CD88) expression correlates with amyloid-beta deposition in murine models of Alzheimer's disease.J Neurochem. 113: 389-401

技术参数

产品应用 Flow Cytometry

产品类型单克隆抗体

推荐用于 Flow Cytometry

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Rat anti mouse CD88:PE 伯乐 CD88抗体 MCA2457PE

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