Mouse anti Human CD177 antibody, clone MEM-166 BIO-RAD MCA2045APC Mouse anti Human CD177 antibody, clone MEM-166

2024-10-29

Mouse anti Human CD177 antibody, clone MEM-166

货号:MCA2045APC

规格:100 Tests

市场价格:3893

产品类型:流式抗体

品牌:Bio-Rad

抗原:CD177

物种:人

宿主:小鼠

抗体亚型:IgG1

克隆号:MEM-166

荧光染料:APC

产品介绍
Mouse anti Human CD177 antibody, clone MEM-166recognizes human CD177 (neutrophil glycoprotein NB1). The neutrophil NB1 antigen is expressed by 97% of the caucasian population. Antibodies against NB1 have been implicated in the pathology of neonatal alloimmune neutropenia (Lalezariet al.1971).
产品详情
Target SpeciesHuman
Product FormPurified IgG conjugated to Allophycocyanin (APC) - lyophilized
PreparationPurified IgG prepared by affinity chromatography on Protein A
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.09% Sodium Azide (NaN3)1% Bovine Serum Albumin
Max Ex/EmFluorophoreExcitation Max (nm)Emission Max (nm)
APC650661
Approx. Protein ConcentrationsIgG concentration 0.1 mg/ml
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application NameVerifiedMin DilutionMax Dilution
Flow CytometryNeat
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Caruccio, L.et al.(2003) Expression of human neutrophil antigen-2a (NB1) is increased in pregnancy.Transfusion. 43 (3): 357-63.2.Kissel, K.et al.(2002) Molecular basis of NB1 (HNA-2a, CD177) deficiency.Blood. 99 (11): 4231-3.3.Jerke, U.et al.(2011) Complement receptor Mac-1 is an adaptor for NB1 (CD177)-mediated PR3-ANCA neutrophil activation.J Biol Chem. 286 (9): 7070-81.4.Dillon, M.et al.(2008) Expression of the GPI-anchored receptor Prv-1 enhances thrombopoietin and IL-3-induced proliferation in hematopoietic cell lines.Leuk Res. 32: 811-9.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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