Rat anti Mouse CD11a antibody, clone I21/7 伯乐MCA1368GT CD11a抗体-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rat anti Mouse CD11a antibody, clone I21/7 伯乐MCA1368GT CD11a抗体

2024-10-29

Rat anti Mouse CD11a antibody, clone I21/7

货号：MCA1368GT,MCA1368G

规格：25 µg,0.25 mg

市场价格：825,3043

产品类型：流式抗体

品牌：Bio-Rad

抗原：CD11a

物种：小鼠

宿主：大鼠

抗体亚型：IgG2a

克隆号：I21/7

荧光染料：Purified

产品介绍
Rat anti Mouse CD11a antibody, clone I21/7recognizes murine CD11a, a ~170-180 kDa type I membrane glycoprotein, also known as the integrin alpha L subunit. CD11a is a member of the integrin family of adhesion molecules. CD11a is expressed on all leucocytes and associates with CD18 to form a heterodimer at the cell surface. The CD11a/CD18 heterodimer binds to intercellular adhesion molecules (ICAM); ICAM1, ICAM-2 and ICAM-3 and is involved in cell-cell adhesion processes.Rat anti Mouse CD11a antibody, clone I21/7 is reported to block the cytolytic activity of cytotoxic T cell lines (Trowbridge and Omary 1981).
产品详情
Target Species	Mouse
Product Form	Purified IgG - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.
BufferSolution	Phosphate buffered saline
Preservative Stabilisers	0.09% Sodium Azide
Carrier Free	Yes
Immunogen	Whole BW5147 cells.
Approx. Protein Concentrations	IgG concentration 1.0mg/ml
Regulatory	For research purposes only
Guarantee	12 monthsfrom date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√
Immunoprecipitation	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications fromthe originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls. Flow Cytometry Use 10ul of the suggested working dilution to label 1 x10⁶cells in 100ul.
同型对照
Description	Product Code	Applications	Pack Size
Rat IgG2a Negative Control	MCA1212	Flow;ELISA	1mL
文献
1. Talento, A.et al.(1993) A single administration of LFA-1 antibody confers prolonged allograft survival.Transplantation. 55 (2): 418-22.2. Campbell, S.B.et al.(2001) CD4 ligation promotes the IL-4-independent development of IL-4-producing clones from naive CD4(+) T cells.J Immunol. 167 (10): 5610-9.3. Kleinschnitz, C.et al.(2013) Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature.Blood. 121: 679-6914. Falanga, P.B. & Butcher, E.C. (1991) Late treatment with anti-LFA-1 (CD11a) antibody prevents cerebral malaria in a mouse model.Eur J Immunol. 21 (9): 2259-63.5.Chiu, W.C.et al.(2007) Effect of dietary fish oil supplementation on cellular adhesion molecule expression and tissue myeloperoxidase activity in diabetic mice with sepsis.Br J Nutr. 97 (4): 685-91.6. Xuemei, H.et al.(2020) Mesenchymal stem cell–derived exosomal microRNA-34c-5p ameliorates renal pericyte activation by inhibiting core fucosylationRes Sq 13 Oct [Epub ahead of print].7. Hu, X.et al.(2021) Bone marrow mesenchymal stem cell-derivedexosomal miR-34c-5p ameliorates RIF by inhibitingthe core fucosylation of multiple proteins.Mol Ther. S1525-0016(21)00519-0.

技术参数

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Rat anti Mouse CD11a antibody, clone I21/7 伯乐MCA1368GT CD11a抗体

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