BIO-RAD MCA2523 Mouse anti Human D-Dimer antibody, clone DD1,Mouse anti Human D-Dimer antibody, clone DD1

2024-10-22

Mouse anti Human D-Dimer antibody, clone DD1

货号:MCA2523

规格:0.2 mg

价格:3043

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:D-Dimer

物种:人

宿主:小鼠

抗体亚型:IgG2a

克隆号:DD1

荧光染料:Purified

产品介绍
Mouse anti Human D-Dimer antibody, clone DD1recognizes human D-dimer and high molecular weight fibrin degradation products, but does not cross-react with fibrinogen (D-monomer).D-dimers are the principle degradation products of cross-linked fibrin, released into the bloodstream following the digestion of fibrin clots (thrombus) by the enzyme plasmin, and thus measurement of the level of D-dimer in plasma, can be used as an indication of thrombotic disorders. Conditions in which levels of D-dimer are elevated include deep vein thrombosis (DVT), venous thromboembolism (VTE), cardiovascular disease and disseminated intravascular coagulation (DIC), a possible acute condition arising from surgical operations, septic shock and liver disease.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationPurified IgG prepared by affinity chromatography on Protein A
Buffer SolutionPhosphate buffered saline
ImmunogenHomogenised fibrin clot.
Fusion PartnersSpleen cells from immunized Balb/c mice were fused with cells of the Sp2/0 myeloma cell line
Preservative Stabilisers<0.1% Sodium Azide (NaN3)
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application NameVerifiedMin DilutionMax Dilution
Flow Cytometry1/50
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Kruskal, J.B.et al.(1992) Elevated fibrin-related and fibrinogen-related antigens in patients with liver disease.Hepatology. 16 (4): 920-3.2.Zamolodchikov, D.et al.(2016) The Alzheimer's disease peptide β-amyloid promotes thrombin generation through activation of coagulation factor XII.J Thromb Haemost. 14 (5): 995-1007.3.IbupotoZafar, H.et al.(2014) The Development of Highly Sensitive and Selective Immunosensor Based on Antibody Immobilized ZnO Nanorods for the Detection of D-DimerElectroanalysis. 26 (2): 292-8.4.Georgia-Paraskei, N.et al.(2014) A Selective Immunosensor for D-dimer Based on Antibody Immobilized on a Graphene Electrode with Incorporated Lipid FilmsElectroanalysis. 26 (7): 1522-7.

技术参数

产品应用 Elisa;WB

产品类型 Monoclonal Antibody

推荐用于 Elisa;WB

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