Mouse anti Human CD38: StarBright Violet 670

货号：MCA1019SBV670

规格：100 Tests/0.5ml

价格：4063

产品类型：流式抗体

品牌：Bio-Rad

抗原：CD38

物种：人

宿主：小鼠

抗体亚型：IgG1

克隆号：AT13/5

荧光染料：StarBright Violet 670

类型:	单抗	同型对照：	IgG1
浓度：		用法：	5.0 µL/test(Flow)
免疫原性：	Namalwa human B-cell line.

Mouse anti Human CD38 antibody, clone AT13/5recognizes CD38, also known as ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, 2'-phospho-ADP-ribosyl cyclase, 2'-phospho-ADP-ribosyl cyclase, ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1 or T10. CD38 is a 300 amino acid ~45 kDa single pass type II transmembrane glycoprotein and Mouse anti Human CD38 antibody, clone AT13/5 has a reactivity pattern consistent with other antibodies of the CD38 cluster. CD38 is expressed by plasma cells, monocytes, early lymphoid cells and activated T cells.CD38 is widely used to study the processes of B and T differentiation and activation. CD38 is a multifunctional enzyme involved in calcium signaling and nicotinamide adenine dinucleotide (NAD+) metabolism (de Oliveiraet al.2018).

数据

Figure A. Alexa Fluor 488 conjugated Mouse anti Human CD3 (MCA463A488). Figure B. Alexa Fluor 488 conjugated Mouse anti Human CD3 (MCA463A488) and StarBright Violet 670 conjugated Mouse anti Human CD38 (MCA1019SBV670). All experiments performed on red cell lysed human blood gated on live lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.

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参考文献：

1.Corcione, A.et al.(2009) CX3CR1 is expressed by human B lymphocytes and mediates [corrected] CX3CL1 driven chemotaxis of tonsil centrocytes.PLoS One. 4: e8485.2.Hovden, A.O.et al.(2011) Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses.BMC Immunol. 12: 2.3.Tipping, A.J.et al.(2009) High GATA-2 expression inhibits human hematopoietic stem and progenitor cell function by effects on cell cycleBlood. 113: 2661-72.4.Slyker, J.A.et al.(2012) Acute cytomegalovirus infection is associated with increased frequencies of activated and apoptosis-vulnerable T cells in HIV-1-infected infants.J Virol. 86 (20): 11373-9.5.Slyker, J.A.et al.(2012) The impact of HIV-1 infection and exposure on natural killer (NK) cell phenotype in Kenyan infants during the first year of life.Front Immunol. 3: 399.

技术参数

产品应用 Flow

产品类型 单克隆抗体

推荐用于 Flow

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