Rabbit anti STAT3 (pSer727) antibody AHP2685 bio-rad,Rabbit anti STAT3 (pSer727) antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rabbit anti STAT3 (pSer727) antibody AHP2685 bio-rad,Rabbit anti STAT3 (pSer727) antibody

2024-10-22

Rabbit anti STAT3 (pSer727) antibody

货号：AHP2685

规格：50 µl

价格：3825

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：STAT3 (pSer727)

物种：其它

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti STAT3 (pSer727) antibodyrecognizes signal transducer and activator of transcription 3 (STAT3), also known as acute-phase response factor, when phosphorylated at serine 727. STAT3 is a member of the STAT family of transcription factors, playing a key role in numerous processes including cell differentiation, proliferation and transformation. Phosphorylation of STAT3 at tyrosine 705 leads to homo- or heterodimerization of STAT3 and is a critical phosphorylation site for STAT3 activity (Huanget al.2014).Serine 727 is also a key phosphorylation site of STAT3. Serine 727 is phosphorylated by multiple kinases including mitogen-activated kinases (MAPK), mammalian target of rapamycin kinase (mTOR), cyclin-dependent kinase 5 (CDK5) and nemo-like kinase (NLK) (Wakaharaet al.2012). Controversy exists around the effect of phosphorylation at serine 727 (Wakaharaet al.2012). There are reports that the transcriptional activity of STAT3 coincides with phosphorylation at serine 727. Some reports indicate that the transcriptional activity of STAT3 coincides with phosphorylation at serine 727 (Yokogamiet al.2000). Other reports show STAT3 activation independent of serine 727 (Wakahara et al. 2012). The role of serine 727 is likely dependent on the larger cellular context.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Antiserum Preparation	Antiserum to STAT3 (pSer727) was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.02% Sodium Azide50% Glycerol
Immunogen	Phospho specific-peptide corresponding to residues surrounding serine 727 of human STAT3
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
Store at -20℃Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√	1/500	1/2000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
Description	Product Code	Applications	Pack Size
Goat anti Rabbit IgG (H/L):HRP	STAR124P	C,E,WB	1mg
Goat anti Rabbit IgG (Fc):Biotin	STAR121B	E,WB	1mg

技术参数

产品应用 wb

产品类型 Polyclonal Antibody

推荐用于 wb

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Rabbit anti STAT3 (pSer727) antibody AHP2685 bio-rad,Rabbit anti STAT3 (pSer727) antibody

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