Rabbit anti PPAR alpha antibody AHP1271 bio-rad,Rabbit anti PPAR alpha antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rabbit anti PPAR alpha antibody AHP1271 bio-rad,Rabbit anti PPAR alpha antibody

2024-10-22

Rabbit anti PPAR alpha antibody

货号：AHP1271

规格：50 µg

价格：3545

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：PPAR alpha

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti PPAR alpha antibodydetects an epitope within the N-terminal region of human peroxisome proliferator-activated receptor, alpha (PPARA), a member of the nuclear hormone receptor subfamily. Upon activation, PPARA forms heterodimers with retinoid X receptors (RXRs), and functions to regulate transcription of specific gene sequences. In particular, PPARA controls genes involved in the peroxisomal and mitochondrial beta oxidation pathways, fatty acid uptake, and triglyceride catabolism in the liver and skeletal muscle.PPARA also has anti-inflammatory and anti-proliferative effects and prevents the proatherogenic effects of cholesterol accumulation in macrophages by stimulating cholesterol efflux.PPARA is the main target of fibrate drugs; hypolipidemic agents used in the treatment of dyslipidemia and the prevention of cardiovascular disease. They could also be used for the treatment of type II diabetes.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Antiserum Preparation	Antisera to human PPAR alpha were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared from whole serum by affinity chromatography.
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	<0.1% Sodium Azide (NaN3)
Immunogen	Synthetic peptide corresponding to amino acids 1-18 of human PPAR alpha.
Approx. Protein Concentrations	IgG concentration 0.98mg/ml
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√	1/500	1/1000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
Description	Product Code	Applications	Pack Size
Goat anti Rabbit IgG (Fc):Biotin	STAR121B	E,WB	1mg
Goat anti Rabbit IgG (H/L):HRP	STAR124P	C,E,WB	1mg
文献
1.Haluzík, M.M. & Haluzík, M. (2006) PPAR-alpha and insulin sensitivity.Physiol Res. 55 (2): 115-22.2.Lefebvre, P.et al.(2006) Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis.J Clin Invest. 116 (3): 571-80.

技术参数

产品应用 elisa；wb

产品类型 Polyclonal Antibody

推荐用于 elisa；wb

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Rabbit anti PPAR alpha antibody AHP1271 bio-rad,Rabbit anti PPAR alpha antibody

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