Rabbit anti PPRAD antibody AHP1272 bio-rad,Rabbit anti PPRAD antibody

2024-10-22

Rabbit anti PPRAD antibody

货号:AHP1272

规格:0.1 mg

价格:4123

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:PPRAD

物种:其它

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti PPRAD antibodydetects peroxisome proliferator-activated receptor, delta (PPARD), a member of the nuclear hormone receptor subfamily. Upon activation, PPARD forms heterodimers with retinoid X receptors (RXRs), and functions to regulate transcription of specific gene sequences. PPARD controls genes involved in lipid metabolism, and enhances fatty acid catabolism and energy uncoupling in adipose tissue and skeletal muscle.PPARD has also been implicated in the proliferation and differentiation of preadipocytes, enterocytes, keratinocytes and the placenta.PPARD agonists could be used therapeutically to target multiple components of the metabolic syndrome, including insulin resistance, hyperglycemia, dyslipidemia, and atherosclerosis.
产品详情
Target SpeciesMouse
Product FormPurified IgG - liquid
Antiserum PreparationAntisera to PPAR delta were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared from whole serum by affinity chromatography.
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers<0.1% Sodium Azide (NaN3)
ImmunogenSyntetic peptide corresponding to amino acids 1-14 of mouse PPAR delta.
Approx. Protein ConcentrationsIgG concentration 1.0 mg/ml
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting1/5001/2000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
DescriptionProduct CodeApplicationsPack Size
Goat anti Rabbit IgG (Fc):BiotinSTAR121BE,WB1mg
Goat anti Rabbit IgG (H/L):HRPSTAR124PC,E,WB1mg
文献
1.Luquet, S.et al.(2005) Roles of PPAR delta in lipid absorption and metabolism: a new target for the treatment of type 2 diabetes.Biochim Biophys Acta. 1740 (2): 313-7.2.Barish, G.D.et al.(2006) PPAR delta: a dagger in the heart of the metabolic syndrome.J Clin Invest. 116 (3): 590-7.3.Grimaldi, P.A. (2005) Regulatory role of peroxisome proliferator-activated receptor delta (PPAR delta) in muscle metabolism. A new target for metabolic syndrome treatment?Biochimie. 87 (1): 5-8.

技术参数

产品应用 elisa;wb

产品类型 Polyclonal Antibody

推荐用于 elisa;wb

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