Rabbit anti Rat NMDA receptor NR2B (pTyr1252) antibody ,Rabbit anti Rat NMDA receptor NR2B (pTyr1252) antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rabbit anti Rat NMDA receptor NR2B (pTyr1252) antibody ,Rabbit anti Rat NMDA receptor NR2B (pTyr1252) antibody

2024-10-22

Rabbit anti Rat NMDA receptor NR2B (pTyr1252) antibody

货号：AHP1235

规格：0.1 ml

价格：6095

产品类型：免疫组化一抗

品牌：Bio-Rad

物种：其它

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti Rat NMDA receptor NR2B (pTyr1252) antibodyrecognizes NMDA receptor NR2B, also known as glutamate receptor ionotropic, NMDA 2B (GluN2B), glutamate [NMDA] receptor subunit epsilon-2 and N-methyl D-aspartate receptor subtype 2B (NMDAR2B), when phosphorylated at tyrosine 1252.Receptors for NMDA belong to a group of ionotropic glutamate receptors which play a key role in the mediation of glutamate neurotransmission within the mammalian central nervous system (CNS), including involvement in memory and learning processes. Several antagonists and agonists of NMDA receptors (NMDAR) have been identified, including the glutamate analogue Homoquinolinic acid, which displays a higher affinity for NR2B-containing NMDAR. Properties of NMDAR include modulation by glycine, inhibition by Zn2+, voltage-dependent Mg2+ blockade and high Ca2+permeability.The involvement of NMDAR in the CNS implicated in neurodegenerative diseases such as Alzheimer's (Popke 2003) and also epilepsy and ischemic neuronal cell death.
产品详情
Target Species	Rat
Product Form	Purified IgG - liquid
Antiserum Preparation	Antisera to rat NMDAR NR2B subunit pTyr1252 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Buffer Solution	10 mM Hepes pH7.5
Preservative Stabilisers	0.09%Sodium Azide (NaN3)50%Glycerol0.01%Bovine Serum Albumin
Immunogen	Phosphopeptide corresponding to smino acid residues surrounding the phosphorylated tyrosine 1252 of the NR2B subunit of rat NMDA receptor.
Approx. Protein Concentrations	IgG concentration 0.5mg/ml
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
ELISA	√		1/1000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
Description	Product Code	Applications	Pack Size
Goat anti Rabbit IgG (Fc):Biotin	STAR121B	E,WB	1mg
Goat anti Rabbit IgG (H/L):HRP	STAR124P	C,E,WB	1mg
文献
1.Ishii, T.et al.(1993) Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits.J Biol Chem. 268 (4): 2836-43.2.Takasu, M.A.et al.(2002) Modulation of NMDA receptor-dependent calcium influx and gene expression through EphB receptors.Science. 295 (5554): 491-5.3.Rosenblum, K.et al.(1996) Long-term potentiation increases tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit 2B in rat dentate gyrus in vivo.Proc Natl Acad Sci U S A. 93 (19): 10457-60.4.Popke, E.J. (2003) From anticholinesterase toxicity to Alzheimer's disease: important interactions of cholinergic and NMDA receptor systems.Toxicol Sci. 72 (2): 185-7.

技术参数

产品应用 wb

产品类型 Polyclonal Antibody

推荐用于 wb

© bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：https://gibcohyclone.cn/thread-42707.htm

特别声明：以上内容(如有图片亦包括在内)来源于授权厂家或网络，如有侵权，请联系删除，本平台不提供信息存储服务。

Notice: The content above (including the pictures if any)comes from authorized manufacturers or networks. In case of infringement, please contact to delete it. This platform does not provide information storage services.

产品询价需求提交

Rabbit anti Rat NMDA receptor NR2B (pTyr1252) antibody ,Rabbit anti Rat NMDA receptor NR2B (pTyr1252) antibody

相关推荐