Goat anti Human SDF-1 beta antibody AHP1211 bio-rad,Goat anti Human SDF-1 beta antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Goat anti Human SDF-1 beta antibody AHP1211 bio-rad,Goat anti Human SDF-1 beta antibody

2024-10-22

Goat anti Human SDF-1 beta antibody

货号：AHP1211

规格：0.1 mg

价格：4063

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：SDF-1 beta

物种：人

宿主：山羊

抗体亚型：IgG

荧光染料：Purified

产品介绍
Goat anti Human SDF-1 beta antibodyrecognizes human SDF-1 beta, otherwise known as CXCL12b, a 72 amino acid stromal cell derived CXC chemokine, which arises from alternative splicing of the SDF-1 gene. The two isoforms, SDF-1 alpha and SDF-1 beta, share an identical amino acid sequence, except for an additional four residues in the C-Terminal region of the beta isoform.SDF-1 binds with high-affinity to the G protein–coupled receptor CXCR4 (fusin) and acts as a chemoattractant for T and B lymphocytes, monocytes and migratory neurons, and is a vital factor in haematopoiesis and angiogenesis. By competitively binding to CXCR4, SDF-1 acts as an inhibitor for the CXCR4-mediated entry of HIV-1 virus into target T-cells, and the SDF-1-CXCR4 interaction is important for the regulation of trafficking of normal and malignant stem cells.
产品详情
Target Species	Human
Product Form	Purified IgG - lyophilized
Reconstitution	Reconstitute with 0.1 ml distilled water. For long term storage the addition of 0.09% sodium azide is recommended.
Antiserum Preparation	Antisera to human SDF-1 beta were raised by repeated immunisations of goats with highly purified antigen. Purified IgG prepared by affinity chromatography.
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	None present.
Immunogen	Recombinant human SDF-1 beta.
Approx. Protein Concentrations	IgG concentration 1.0 mg/ml
Regulatory	For research purposes only
Guarantee	3 months from date of reconstitution. Please see label for expiry date.
存储条件
Prior to reconstitution store at -20°C.After reconstitution store at -20°C.This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application Name	Verified	Min Dilution	Max Dilution
ELISA	√		0.5ug/ml
Western Blotting	√	0.1	0.2ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
Description	Product Code	Applications	Pack Size
Rabbit anti Goat IgG (Fc):FITC	STAR122F	F	100 Tests
Rabbit anti Goat IgG (Fc):HRP	STAR122P	C,E,WB	100 Tests
文献
1.Nagasawa, T.et al.(1998) A novel CXC chemokine PBSF/SDF-1 and its receptor CXCR4: their functions in development, hematopoiesis and HIV infection.Semin Immunol. 10 (3): 179-85.2.Stumm, R. & Höllt, V. (2007) CXC chemokine receptor 4 regulates neuronal migration and axonal pathfinding in the developing nervous system: implications for neuronal regeneration in the adult brain.J Mol Endocrinol. 38 (3): 377-82.3.Kucia, M.et al.(2005) Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axis.Stem Cells. 23 (7): 879-94.

技术参数

产品应用 elisa；wb

产品类型 Polyclonal Antibody

推荐用于 elisa；wb

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Goat anti Human SDF-1 beta antibody AHP1211 bio-rad,Goat anti Human SDF-1 beta antibody

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