Bio-Rad AAM74 CD289,Goat anti Mouse CD289 antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Bio-Rad AAM74 CD289,Goat anti Mouse CD289 antibody

2024-10-22

Goat anti Mouse CD289 antibody

货号：AAM74

规格：0.1 mg

价格：4420

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：CD289

物种：小鼠

宿主：山羊

抗体亚型：IgG

荧光染料：Purified

产品介绍
Goat anti Mouse CD289 antibodyrecognises murine Toll-like receptor 9, also known as CD289 or TLR9. CD289 is an 1032 amino acid ~120 kDa endosomal single pass type I transmembrane glycoprotein with a number ofleucine rich repeatsand a singleTIRdomain (UniProt: Q9NR96). Goat anti Mouse CD289 antibody recognizes an epitope within the N-terminal (NT) region of CD289, a member of the toll-like receptor family, which triggers MyD88 and TRAF6, resulting in NF-kappaB activation, cytokine secretion and the inflammatory response.CD289 acts as a receptor for unmethylated cytidine-phosphate-guanosine dinucleotides in bacterial DNA (CpG-DNA), playing a primary role in pathogen recognition and activation of innate immunity and has been shown to play a role in defence against systemic mouse cytomegalovirus infection.Goat anti Mouse CD289 antibody is reported as suitable for use in immunocytochemistry on acetone fixed cells.
产品详情
Target Species	Mouse
Product Form	Purified IgG - liquid
Antiserum Preparation	Antiserum to mouse CD289 (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	<0.1% Sodium Azide (NaN₃)0.1% Bovine Serum Albumin
Approx. Protein Concentrations	IgG concentration 1.0mg/ml
Immunogen	Synthetic peptide LSLKYNNLTKVPRQLPPSLEY-C corresponding to amino acids 204-224 within the N-terminal region of mouse CD289.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
Store at -20℃only.Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application Name	Verified	Min Dilution	Max Dilution
Immunohistology - Paraffin	√	1:125
Western Blotting	√	1:500
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.Histology Positive Control TissueSpleen, thymus or tonsil
二抗相关产品
Description	Product Code	Applications	Pack Size
Rabbit anti Goat IgG (Fc):FITC	STAR122F	Flow	1 mg
Rabbit anti Goat IgG (Fc):HRP	STAR122P	C;E;WB	1 mg
数据
Staining of paraffin embedded mouse thymus with Goat anti mouse CD289 (AAM74).
文献
1. Ripoll, V.M.et al.(2010) Macrophages from BALB/c and CBA/Ca mice differ in their cellular responses toStreptococcus pneumoniae.J Leukoc Biol. 87: 735-41.

技术参数

产品应用 IHC(P);WB

产品类型 Polyclonal Antibody

推荐用于 IHC(P);WB

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Bio-Rad AAM74 CD289,Goat anti Mouse CD289 antibody

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