Bio-Rad CD273抗体 AHP1704,Rabbit anti Human CD273-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Bio-Rad CD273抗体 AHP1704,Rabbit anti Human CD273

2024-10-22

Rabbit anti Human CD273

货号：AHP1704

规格：0.1 mg

价格：4862

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原： CD273

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti Human CD273 antibodyrecognizes human CD273, also known as B7-DC and Programmed Death Ligand 2 (PD-L2). CD273 is a single-pass type 1 membrane protein belonging to the immunoglobulin receptor superfamily, and is a ligand for CD279 (PD-1).CD273 is highly expressed in the tissues of the heart, liver, lung, placenta and pancreas. It is expressed in dendritic cells, and its expression can be induced on inflammatory macrophages when activated by interleukin 4 or Th2 cells.CD273 functions to inhibit T-cell proliferation by blocking cell cycle progression and cytokine production, and is particularly important in the maintenance of self tolerance.
产品详情
Target Species	Human
Species Cross-Reactivity	Target SpeciesCross Reactivity
	Mouse√
	Rat √
	N.B. Antibody reactivity and working conditions may vary between species.
Product Form	Purified IgG - liquid
AntiserumPreparation	Antisera to Human CD273 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared from whole serum by affinity chromatography.
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.02% Sodium Azide (NaN₃)
Immunogen	A peptide corresponding to a 16 amino acid sequence from near the centre of Human CD273.
Approx. Protein Concentrations	IgG concentration 1.0mg/ml
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Immunohistology - Paraffin¹	√		2.5ug/ml
Western Blotting	√	0.5	1.0ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage. ¹This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls. Histology Positive Control Tissue Mouse brain tissue Western Blotting AHP1704 detects a band of approximately 30kDa in Raji cell lysate
相关产品
Description	Product Code	Applications	Pack Size
Antigen Retrieval Buffer, pH8.0	BUF025A	P	500 ml
TidyBlot Western Blot Detection Reagent:HRP	STAR209P	WB*	0.5 ml
文献
1.Zhang, Y.et al.(2006) Regulation of T cell activation and tolerance by PDL2.Proc Natl Acad Sci U S A. 103 (31): 11695-700.2.LaGier, A.J. & Pober, J.S. (2006) Immune accessory functions of human endothelial cells are modulated by overexpression of B7-H1 (PDL1).Hum Immunol. 67 (8): 568-78.3.Ishida, Y.et al.(1992) Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.EMBO J. 11 (11): 3887-95.4.Holling, T.M.et al.(2004) Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men.Hum Immunol. 65 (4): 282-90.

技术参数

产品应用 P*;WB

产品类型 Polyclonal Antibody

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Bio-Rad CD273抗体 AHP1704,Rabbit anti Human CD273

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