TAL1 Polyclonal Antibody

货号：PA5-30586

规格：100 µL

价格：4880

产品类型：抗体和染料

品牌：Thermo Fisher

物种：人/小鼠

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	单抗	同型对照：
浓度：	0.99 mg/mL	用法：	1:500-1:3,000 (WB)；1:100-1:1,000(IHC (P))；1:100-1:500 (IP)

产品详细信息Recommended positive controls: H1299.Predicted reactivity: Bovine (100%).Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.靶标信息TAL-1 is a basic helix-loop-helix transcription. It regulates differentiation and survival during hemopoiesis. TAL-1 is also implicated in the genesis of hemopoietic malignancies and it may play an important role in hemopoietic differentiation. It serves as a positive regulator of eryhtroid differentiation. Mutations are associated with T-cell leukemia and melanoma. TAL-1 is know to bind to the LIM domain containing protein Rhombotin-2.

数据

TAL1 Antibody (PA5-30586) in IHC (P)Immunohistochemical analysis of TAL1 in the cytosol and nucleus of paraffin-embedded mouse spleen tissue using a TAL1 polyclonal antibody (Product # PA5-30586) at a dilution of 1:500.

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参考文献：

1.Scientific reportsDengue virus infection impedes megakaryopoiesis in MEG-01 cells where the virus envelope protein interacts with the transcription factor TAL-1."PA5-30586 was used in Immunoprecipitation to establish an in vitro model of platelet production from MEG-01 cells and show that DENV infection alters the megakaryopoiesis in these cells leading to the lowering of platelet numbers."2.Scientific reportsDengue virus infection impedes megakaryopoiesis in MEG-01 cells where the virus envelope protein interacts with the transcription factor TAL-1."PA5-30586 was used in Immunoprecipitation to establish an in vitro model of platelet production from MEG-01 cells and show that DENV infection alters the megakaryopoiesis in these cells leading to the lowering of platelet numbers."3.Scientific reportsDengue virus infection impedes megakaryopoiesis in MEG-01 cells where the virus envelope protein interacts with the transcription factor TAL-1."PA5-30586 was used in Immunoprecipitation to establish an in vitro model of platelet production from MEG-01 cells and show that DENV infection alters the megakaryopoiesis in these cells leading to the lowering of platelet numbers."

技术参数

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