CD38 Monoclonal Antibody (HIT2), FITC

货号：MHCD3801,MHCD3801-4

规格：0.5ml,2ml

价格：3437,11470

产品类型：流式抗体

品牌：Thermo Fisher

物种：人

宿主：小鼠

抗体亚型：IgG1

克隆号：HIT2

荧光染料：FITC

类型:	单抗	同型对照：
浓度：		用法：	Assay-Dependent(Flow)

产品详细信息Commonly used, FITC conjugates provide relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility.靶标信息CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. CD38 functions as a multi-catalytic ectoenzyme serving as ADP-ribosyl cyclase, cyclic ADP-ribose hydrolase and possibly NAD+ glycohydrolase or as a cell surface receptor. Antibodies to CD38 are useful in subtyping of lymphomas and leukemias, detection of plasma cells (i.e. identification of myelomas), and as a marker for activated B and T cells. CD38 participates in cell adhesion, signal transduction and calcium signaling. Further, CD38 is expressed at high levels in the pancreas, liver, kidney, malignant lymphoma and neuroblastoma. Diseases associated with CD38 dysfunction include chronic lymphocytic leukemia and Richter's Syndrome.

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参考文献：

1.ImmunologyRole of CD8(+) T cells in triggering reversal reaction in HIV/leprosy patients."MHCD3801 was used in Flow cytometry/Cell sorting to study the role of CD8(+) T cells in triggering reversal reaction in HIV/leprosy patients."2.Experimental hematologyIdentification of four human cDNAs that are differentially expressed by early hematopoietic progenitors."MHCD3801 was used in flow cytometry to elucidate the molecular processes that maintain the stem cell pool."3.Journal of immunology (Baltimore, Md. : 1950)Expression, regulation, and function of B cell-expressed CD154 in germinal centers."MHCD3801 was used in flow cytometry to investigate the expression and function of B cell CD154."4.British journal of haematologyDifferent behaviour of fresh and cultured CD34+ cells during immunomagnetic separation."MHCD3801 was used in flow cytometry to characterize CD34+ cells derived from human cord blood after culture."5.Photochemistry and photobiologyCharacterization of endogenous protoporphyrin IX induced by delta-aminolevulinic acid in resting and activated peripheral blood lymphocytes by four-color flow cytometry."MHCD3801 was used in flow cytometry to determine the effects of delta-aminolevulinic acid and delta-aminolevulinic acid-photodynamic therapy on resting and activated human peripheral blood T lymphocytes."

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