Cytokeratin 5 Monoclonal Antibody (2C2)

货号：MA5-17057

规格：100 µg

价格：4805

产品类型：免疫组化一抗

品牌：Thermo Fisher

抗原：Purified recombinant fragment of human CK5 express

物种：人/小鼠

宿主：小鼠

抗体亚型：其它

克隆号：2C2

荧光染料：其它

类型:	单抗	同型对照：	IgG1
浓度：	1 mg/mL	用法：	1:200 - 1:400(Flow)；1:200 - 1:1000(ICC);1:200 - 1:1000(IF);1:200 - 1:1000(IHC);1:500 - 1:2000(WB)

产品详细信息MA5-17057 targets CK5 in FACS, ICC, IHC, IF and WB applications and shows reactivity with Human, Mouse, and Non-human primate samples.The MA5-17057 immunogen is purified recombinant fragment of human CK5 expressed in E. Coli.MA5-17057 detects CK5 which has a predicted molecular weight of approximately 62.3kDa.靶标信息Cytokeratin pan is part of a subfamily of intermediate filament proteins that are characterized by remarkable biochemical diversity, and represented in human epithelial tissues by at least 20 different polypeptides. Cytokeratins range in molecular weight between 40 kDa- 68 kDa, and an isoelectric pH between 4.9-7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. The composition of cytokeratin pairs vary with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.仅用于科研。不用于诊断过程。未经明确授权不得转售。

数据

Cytokeratin 5 Antibody (MA5-17057) in IFImmunofluorescence analysis of HeLa cells using CK5 monoclonal antibody (Product # MA5-17057). Blue: DRAQ5 fluorescent DNA dye. Red: actin filaments have been labeled with phalloidin. Cytokeratin 5 Antibody (MA5-17057) in IFImmunofluorescence analysis of HeLa cells using CK5 monoclonal antibody (Product # MA5-17057) (Green). Red: actin filaments have been labeled with phalloidin. Cytokeratin 5 Antibody (MA5-17057) in IFImmunofluorescence analysis of HeLa cells using CK5 monoclonal antibody (Product # MA5-17057) (Green). Red: actin filaments have been labeled with phalloidin. Cytokeratin 5 Antibody (MA5-17057) in WBWestern blot analysis of CK5 using CK5 monoclonal antibody (Product # MA5-17057) in A431 (1), MCF-7 (2), HeLa (3), HepG2 (4), 3T3-L1 (5), and COS-7 (6) cell lysate. Cytokeratin 5 Antibody (MA5-17057) in FlowFlow cytometric analysis of HeLa cells using CK5 monoclonal antibody (Product # MA5-17057) (green) and negative control (red).

推荐产品：

二抗荧光二抗免疫组化一抗标签抗体

参考文献：

1.Nature communicationsRecurrent hotspot mutations in HRAS Q61 and PI3K-AKT pathway genes as drivers of breast adenomyoepitheliomas.2.Journal of tissue engineering and regenerative medicineUrothelial cell expansion and differentiation are improved by exposure to hypoxia.3.Scientific reportsConditional ablation of TGF-β signaling inhibits tumor progression and invasion in an induced mouse bladder cancer model.

技术参数

© bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：https://gibcohyclone.cn/thread-44847.htm