Human Azurocidin/CAP37/HBP ELISA Kit ELISA试剂盒,Human Azurocidin/CAP37/HBP ELISA Kit/人Azurocidin / CAP37 / HBP ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Human Azurocidin/CAP37/HBP ELISA Kit ELISA试剂盒,Human Azurocidin/CAP37/HBP ELISA Kit/人Azurocidin / CAP37 / HBP ELISA试剂盒

2024-10-24

Human Azurocidin/CAP37/HBP ELISA Kit/人Azurocidin / CAP37 / HBP ELISA试剂盒

货号：EH39RB,EH39RBX5,EH39RBX10

规格：96 tests,5X96 tests,10X96 tests

价格：6641,29884,57271

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：人

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	0.42 ng/mL
检测范围	0.42-100 ng/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	Azurocidin
Protein aliases	Azurocidin, cationic antimicrobial protein 37, Cationic antimicrobial protein CAP37, HBP, Heparin-binding protein, neutrophil azurocidin
物种（Tested）	人
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	AZAMP, AZU, AZU1, CAP37, HBP, hHBP, HUMAZUR, NAZC
Gene ID	(Human) 566
Gene symbol	AZU1
UniProt ID	(Human) P20160

Human Azurocidin/CAP37/HBP quantitates human Azurocidin/CAP37/HBP in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Azurocidin/CAP37/HBP.人Azurocidin / CAP37 / HBP定量测定血清，血浆，上清液中的人Azurocidin / CAP37 / HBP。该检测试剂盒将专门识别天然和重组人天青霉素/ CAP37 / HBP。Target information 靶标信息Azurocidin, also called heparin-binding protein (HBP), is an inactive homolog of serine proteinases residing in granulocytes. Initially it was thought to have only activity against gram-negative bacteria. Later it was also found to act against gram-positive bacteria and C. albicans. Azurocidin is considered a family member of polymorphonuclear leukocytes- derived antimicrobial proteins like defensins, LL-37 and lysozyme. Azurocidin has been recognized as a player in the activation and modulation of the immune response and may act to alarm the immune system. The cationic domain at one side of the protein is essential for its antimicrobial activity. It is stored in azurophil granules as well as secretory granules and as a result partly released at early stage of extravasation. Azurocidin is involved in chemotaxis and activation of monocytes, cytokine release and phagocytosis leading to more efficient bacterial clearance. The primary targeted environment of azurocidin are cells in the bloodstream, that is the endothelial lining, and the extravascular surroundings. The interaction of azurocidin with leucocytes is mediated via beta 2-intergrins. High plasma levels of azurocidin might help with the identification of patients which are at risk in developing sepsis.Azurocidin，也称为肝素结合蛋白（HBP），是粒细胞中丝氨酸蛋白酶的非活性同源物。最初，人们认为它仅对革兰氏阴性菌具有活性。后来还发现它对革兰氏阳性细菌和白色念珠菌有作用。 Azurocidin被认为是多形核白细胞衍生的抗菌蛋白（如防御素，LL-37和溶菌酶）的家族成员。天青霉素已被公认为是免疫反应的激活和调节的参与者，可能会警告免疫系统。蛋白质一侧的阳离子结构域对其抗菌活性至关重要。它被存储在嗜蓝颗粒和分泌颗粒中，因此在外渗早期被部分释放。 Azurocidin参与单核细胞的趋化性和活化，细胞因子的释放和吞噬作用，从而导致更有效的细菌清除。天青霉素的主要靶向环境是血流中的细胞，即内皮层和血管外环境。天青霉素与白细胞的相互作用是通过β2-整合素介导的。血浆高浓度的金青霉素可能有助于鉴定有发生败血症危险的患者。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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Human Azurocidin/CAP37/HBP ELISA Kit ELISA试剂盒,Human Azurocidin/CAP37/HBP ELISA Kit/人Azurocidin / CAP37 / HBP ELISA试剂盒

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