Human CD55/DAF ELISA Kit ELISA试剂盒,Human CD55/DAF ELISA Kit/人CD55 / DAF ELISA试剂盒

2024-10-24

Human CD55/DAF ELISA Kit/人CD55 / DAF ELISA试剂盒

货号:EH93RB,EH93RBX5,EH93RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.85 ng/mL

检测范围0.85-200 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameCD55
Protein aliasesCD55, CD55 antigen, CD55 molecule, decay accelerating factor for complement (Cromer blood group), Complement decay-accelerating factor

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesCD55, CR, CROM, DAF, TC
Gene ID(Human) 1604
Gene symbolCD55
UniProt ID(Human) P08174
Human CD55/DAF quantitates human CD55/DAF in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CD55/DAF.人CD55 / DAF定量检测血清,血浆,上清液中的人CD55 / DAF。该检测试剂盒将专门识别天然和重组人CD55 / DAF。Target information 靶标信息CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can regulate complement when bound to CD97. In tumors, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis. CD55 is a 70 kDa glycoprotein (in erythrocytes) anchored in the membrane by glycosylphosphatidylinositol tail. In other cells, the apparent molecular weight is somewhat larger for CD55 and has a substantial content of O-glycans. CD55 binds to activated C4b or C3b complement fragments on the cell surface, preventing the assembly and accelerating the decay of both classical and alternative pathways. CD55 carries the Cromer related blood group antigens. Two alternatively spliced transcripts encoding CD55 have been identified, and the predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. CD55 has been studied to have a role in prostate cancer growth and survival.CD55(衰变加速因子,DAF)是一种GPI锚定的膜糖蛋白,可保护自体细胞免受补体级联的经典途径和替代途径的侵害。 CD55和CD97之间的双向相互作用涉及T细胞调节,而CD55与CD97结合时可以调节补体。在肿瘤中,CD55促进新血管生成,肿瘤发生,侵袭和细胞凋亡的逃逸。 CD55是一种70 kDa的糖蛋白(在红细胞中),被糖基磷脂酰肌醇尾巴锚定在膜中。在其他细胞中,CD55的表观分子量稍大,并且含有大量的O-聚糖。 CD55与细胞表面活化的C4b或C3b补体片段结合,从而防止组装并加速经典途径和替代途径的衰变。 CD55带有Cromer相关的血型抗原。已经鉴定出两个编码CD55的选择性剪接的转录本,并且主要转录本编码在暴露于血浆成分蛋白的细胞上表达的膜结合蛋白,但是选择性剪接的转录本产生的可溶性蛋白水平要低得多。已经研究了CD55在前列腺癌的生长和存活中起作用。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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