组蛋白甲基化修饰,H4K20,多克隆抗体,SUV420H1 Polyclonal Antibody

2024-10-24

SUV420H1 Polyclonal Antibody

货号:PA5-40926

规格:100 µL

价格:4805

产品类型:标签抗体

品牌:Thermo Fisher

抗原:Synthetic peptide directed towards the middle regi

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:其它

类型:一抗同型对照:
浓度: 0.5mg/mL用法:4-8 µg/mL(IHC(P));0.2-2 µg/mL(WB)
产品详细信息Peptide sequence: NNGFNSGSGS SSTKLKIQLK RDEENRGSYT EGLHENGVCC SDPLSLLESRSequence homology: Dog: 86%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 91%; Rat: 93%靶标信息Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2). Plays a role in myogenesis by regulating the expression of target genes, such as EID3.
数据:

SUV420H1 Antibody (PA5-40926) in IHC (P)Immunohistochemistry (paraffin-embedded) analysis of human skin tissue using an anti-SUV420H1 polyclonal antibody (Product # PA5-40926).

SUV420H1 Antibody (PA5-40926) in WBWestern blot analysis of human placenta cells using an anti-SUV420H1 polyclonal antibody (Product # PA5-40926).
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