Canine SCF/KITLG ELISA Kit ELISA试剂盒,Canine SCF/KITLG ELISA Kit/犬SCF / KITLG ELISA试剂盒

2024-10-24

Canine SCF/KITLG ELISA Kit/犬SCF / KITLG ELISA试剂盒

货号:EC16RB,EC16RBX5,EC16RBX10

规格:96 Tests,5X96 Tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:其它

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.065 ng/mL

检测范围0.065-16 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameSCF
Protein aliasesc-Kit ligand, Kit ligand, Mast cell growth factor, MGF, Processed kit ligand, SCF, sKITLG, Soluble KIT ligand, Stem cell factor, stem cell factor, CSF

物种(Tested)

狗

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliases710-712, CSF, KITLG, MGF
Gene ID(Dog) 403507
UniProt ID(Dog) Q06220
Gene symbolKITLG
Canine SCF/KITLG quantitates canine SCF/KITLG in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant canine SCF/KITLG.犬SCF / KITLG定量检测血清,血浆,上清液中的犬SCF / KITLG。 该检测试剂盒将专门识别天然和重组犬SCF / KITLG。Target information 靶标信息Stem cell factor (SCF) is the ligand of the c-Kit oncogene and is expressed by various structural and inflammatory cells in the airways. Binding of SCF by the c-Kit receptor leads to homodimerization of the receptor and the activation of signalling pathways such as PI-3, PLC-gamma, Jak/STAT, and MAP kinase pathways. SCF expression leads to the induction of mast cell survival and the expression and release of histamine, pro-inflammatory cytokines and chemokines. The inhibition of the SCF/c-Kit pathway leads to a decrease in histamine levels, mast cell and eosinophil infiltration, IL-4 production and airway hyperresponsiveness, suggesting this pathway may be a useful therapeutic target in inflammatory diseases such as asthma. At least two isoforms of SCF are known to exist.干细胞因子(SCF)是c-Kit癌基因的配体,由气道中的各种结构细胞和炎症细胞表达。 c-Kit受体与SCF的结合导致该受体的同二聚化,并激活诸如PI-3,PLC-γ,Jak / STAT和MAP激酶等信号通路。 SCF的表达导致肥大细胞存活的诱导以及组胺,促炎细胞因子和趋化因子的表达和释放。 SCF / c-Kit途径的抑制导致组胺水平降低,肥大细胞和嗜酸性粒细胞浸润,IL-4产生以及气道高反应性降低,表明该途径可能是炎性疾病(例如哮喘)的有用治疗靶标。 已知存在至少两个SCF同工型。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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