MRG15 Polyclonal Antibody

货号：PA5-78349

规格：100 µL

价格：5817

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Recombinant protein encompassing a sequence within

物种：其它

宿主：山羊

抗体亚型：IgG

荧光染料：Alexa Fluor 488

类型:	一抗	同型对照：
浓度：	1.83mg/mL	用法：	1:100-1:1000（ICC）；1:100-1:1000(ICC);1:500-1:3000(WB)

产品详细信息Positive Control: Huh7, Hep3B, mouse liverPredicted Reactivity: Rat (100%), Zebrafish (91%), Xenopus laevis (92%), Rabbit (100%), Chicken (98%), Rhesus Monkey (100%), Bovine (99%)Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.靶标信息MRG15 ia a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis and DNA repair.

数据：

MRG15 Antibody (PA5-78349) in IFImmunofluorescent analysis of MRG15 in HeLa cells. Samples were treated with 4% paraformaldehyde at RT for 15 min and incubated with MRG15 polyclonal antibody (Product # PA5-78349) using a dilution of 1:1000, followed by Hoechst. MRG15 Antibody (PA5-78349) in WBWestern blot analysis of MRG15 in A) Huh7 whole cell lysate, B) Hep3B whole cell lysate using 30 µg of protein. Samples were separated with 10% SDS-PAGE and incubated with MRG15 polyclonal antibody (Product # PA5-78349) using a dilution of 1:500.

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