Mouse MCAM/CD146 ELISA Kit ELISA试剂盒,Mouse MCAM/CD146 ELISA Kit/小鼠MCAM / CD146 ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Mouse MCAM/CD146 ELISA Kit ELISA试剂盒,Mouse MCAM/CD146 ELISA Kit/小鼠MCAM / CD146 ELISA试剂盒

2024-10-24

Mouse MCAM/CD146 ELISA Kit/小鼠MCAM / CD146 ELISA试剂盒

货号：EM52RB,EM52RBX5,EM52RBX10

规格：96 Tests,5X96 Tests,10X96 tests

价格：6641,29884,57271

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：小鼠

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	0.18 ng/mL
检测范围	0.18-40 ng/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	CD146
Protein aliases	CD146, Cell surface glycoprotein MUC18, Gicerin, l-gicerin protein, melanoma adhesion molecule, Melanoma cell adhesion molecule, Melanoma-associated antigen MUC18
物种（Tested）	小鼠
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	1-gicerin, AV025631, CD146, CD149, Mcam, Muc18, s-endo, s-gicerin
Gene ID	(Mouse) 84004
Gene symbol	Mcam
UniProt ID	(Mouse) Q8R2Y2

Mouse MCAM/CD146 quantitates mouse MCAM/CD146 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse MCAM/CD146.小鼠MCAM / CD146定量测定血清，血浆，上清液中的小鼠MCAM / CD146。该检测试剂盒将专门识别天然和重组小鼠MCAM / CD146。Target information 靶标信息CD146 (MCAM) is an integral membrane glycoprotein belonging to the immunoglobulin superfamily. CD146 is expressed at cell-cell junctions in all endothelial cells, and has also been observed in other normal and malignant cell types. In addition to its recognized role as a calcium-independent cell adhesion molecule, CD146 may also act as a signal transduction molecule in the recruitment of Fyn kinase, and in the subsequent tyrosine-phosphorylation of intracellular proteins involved in actin cytoskeleton assembly. CD146 plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. CD146 expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Further, CD146 could be an adhesion molecule active in neural crest cells during embryonic development. CD146 acts also as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.CD146（MCAM）是属于免疫球蛋白超家族的完整膜糖蛋白。 CD146在所有内皮细胞的细胞-细胞连接处表达，并且在其他正常和恶性细胞类型中也已观察到。除了其作为钙依赖性细胞粘附分子的公认作用外，CD146还可以在Fyn激酶募集以及随后的肌动蛋白细胞骨架组装所涉及的细胞内蛋白酪氨酸磷酸化中充当信号转导分子。 CD146在细胞粘附以及血管组织中细胞间连接处的内皮单层粘附中发挥作用。 CD146表达可能使黑色素瘤细胞与血管系统的细胞成分相互作用，从而增强血源性肿瘤扩散。此外，CD146可能是胚胎发育过程中在神经c细胞中活跃的粘附分子。 CD146还充当表面受体，触发FYN和PTK2的酪氨酸磷酸化，并引起细胞内钙浓度的瞬时增加。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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Mouse MCAM/CD146 ELISA Kit ELISA试剂盒,Mouse MCAM/CD146 ELISA Kit/小鼠MCAM / CD146 ELISA试剂盒

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