Mouse Neprilysin ELISA Kit ELISA试剂盒,Mouse Neprilysin ELISA Kit/小鼠脑啡肽ELISA试剂盒

2024-10-24

Mouse Neprilysin ELISA Kit/小鼠脑啡肽ELISA试剂盒

货号:EM55RB,EM55RBX5,EM55RBX10

规格:96 Tests,5X96 Tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:小鼠

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

61 pg/mL

检测范围61-15,000 pg/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameCD10
Protein aliasesAtriopeptidase, CD10, common acute lymphoblastic leukemia antigen, Enkephalinase, NEP, Neprilysin, Neutral endopeptidase 24.11, SFE, Skin fibroblast elastase

物种(Tested)

小鼠

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliases6030454K05Rik, C85356, CALLA, CD10, Mme, NEP, SFE
Gene ID(Mouse) 17380
Gene symbolMme
UniProt ID(Mouse) Q61391
Mouse Neprilysin quantitates mouse Neprilysin in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse Neprilysin.小鼠脑啡肽酶定量测定血清,血浆,上清液中的小鼠脑啡肽酶。该检测试剂盒将只识别天然和重组小鼠脑啡肽酶。Target information 靶标信息CD10 (Common Acute Lymphocytic Leukemia Antigen, CALLA), is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, immature B cells with in adult bone marrow and on cells from patients with chronic myelocytic leukemia (CML). CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells. CD10 is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. Further, CD10 is a 100 kDa type II transmembrane glycoprotein that exists in a single copy of greater than 45 kb. The 5' untranslated region of the CD10 gene is alternatively spliced, resulting in four separate mRNA transcripts and the coding region is not affected by alternative splicing. Diseases associated with CD10 dysfunction include spinocerebellar ataxia 43 and Charcot-Marie tooth Disease.CD10(普通急性淋巴细胞白血病抗原,CALLA)是一种具有中性金属内肽酶活性的细胞表面酶,可以使多种生物活性肽失活。 CD10在成年骨髓的淋巴母细胞,伯基特氏和滤泡生发中心淋巴瘤,未成熟的B细胞以及慢性粒细胞性白血病(CML)患者的细胞上表达。 CD10也存在于乳腺肌上皮细胞,胆小管,成纤维细胞上,在肾脏和肠上皮细胞的刷状缘特别高表达。 CD10是一种中性内肽酶,可在疏水残基的氨基端切割肽,并使几种肽激素失活,包括胰高血糖素,脑啡肽,P物质,神经降压素,催产素和缓激肽。另外,CD10是100kDa的II型跨膜糖蛋白,以大于45kb的单拷贝存在。交替剪接CD10基因的5'非翻译区,产生四个独立的mRNA转录本,编码区不受交替剪接的影响。与CD10功能障碍有关的疾病包括脊髓小脑共济失调43和Charcot-Marie牙齿病。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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