Mouse VISTA/B7-H5/PD-1H ELISA Kit ELISA试剂盒,Mouse VISTA/B7-H5/PD-1H ELISA Kit/小鼠VISTA / B7-H5 / PD-1H ELISA试剂盒

2024-10-24

Mouse VISTA/B7-H5/PD-1H ELISA Kit/小鼠VISTA / B7-H5 / PD-1H ELISA试剂盒

货号:EM74RB,EM74RBX5,EM74RBX10

规格:96 Tests,5X96 Tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:小鼠

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

3 ng/mL

检测范围3-600 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameVISTA
Protein aliasesdifferentiation of ESCs 1, Platelet receptor Gi24, V-set domain-containing immunoregulatory receptor, V-set immunoregulatory receptor, V-type immunoglobulin domain-containing suppressor of T-cell activation

物种(Tested)

小鼠

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesDies1, PD-1H, VISTA, Vsir
Gene ID(Mouse) 74048
Gene symbol4632428N05Rik
UniProt ID(Mouse) Q9D659
Mouse VISTA/B7-H5/PD-1H quantitates mouse VISTA/B7-H5/PD-1H in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse VISTA/B7-H5/PD-1H.小鼠VISTA / B7-H5 / PD-1H定量测定血清,血浆,上清液中的小鼠VISTA / B7-H5 / PD-1H。 该检测试剂盒将专门识别天然和重组小鼠VISTA / B7-H5 / PD-1H。Target information 靶标信息VISTA (V-domain Ig containing suppressor of T-cell activation), also known as B7-H5 or PD-1H, is a product of the VSIR gene. Although VISTA bears sequence homology to PD-L1 it has a different expression pattern. In both mouse and humans, VISTA is expressed predominantly on hematopoietic cells with the highest densities on myeloid cells, and lower levels on T cells. It is usually absent on B cells. VISTA expressed by antigen presenting cells has been shown to directly suppress proliferation and cytokine production of CD4 and CD8 T cells, making it a target for cancer immunotherapy. The reported ligands of VISTA include CD28H, VSIG-3 and VSIG-8.VISTA(含有T细胞活化抑制剂的V结构域Ig),也称为B7-H5或PD-1H,是VSIR基因的产物。 尽管VISTA与PD-L1具有序列同源性,但它具有不同的表达模式。 在小鼠和人中,VISTA主要在造血细胞上表达,其在髓样细胞上的密度最高,而在T细胞上的水平较低。 通常在B细胞上不存在。 抗原呈递细胞表达的VISTA已显示可直接抑制CD4和CD8 T细胞的增殖和细胞因子的产生,使其成为癌症免疫疗法的靶标。 报道的VISTA配体包括CD28H,VSIG-3和VSIG-8。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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