Rabbit anti Human XIAP antibody BIO-RAD VPA00699 Rabbit anti Human XIAP antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rabbit anti Human XIAP antibody BIO-RAD VPA00699 Rabbit anti Human XIAP antibody

2024-10-28

Rabbit anti Human XIAP antibody

货号：VPA00699

规格：100μl

市场价格：4097

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：XIAP

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti Human XIAP antibodyrecognizes the E3 ubiquitin-protein ligase XIAP, also known as XIAP, XLP2, BIRC5 or MIHA.The XIAP gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein, BIRC5, functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. MIHA also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in XIAP are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of XIAP are found on chromosomes 2 and 11 (provided by RefSeq, Feb 2011).Rabbit anti Human XIAP antibody detects a band of 53 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution	Phosphate buffered saline.
Preservative Stabilisers	0.01% Thiomersal<50% Glycerol
Immunogen	Recombinant protein encompassing part of the C-terminal region of human XIAP
Approx. Protein Concentrations	IgG concentration 0.5 mg/ml.
Acknowledgements	PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch.
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√	1/1000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.Flow CytometryUse 10ul of the suggested working dilution to label 106cells or 100ul human whole blood.
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技术参数

产品应用 wb

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Rabbit anti Human XIAP antibody BIO-RAD VPA00699 Rabbit anti Human XIAP antibody

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