Mouse anti Human tissue factor pathway inhibitor antibody, clone OTI4H9 BIO-RAD VMA00293 Mouse anti Human tissue factor pa

2024-10-28

Mouse anti Human tissue factor pathway inhibitor antibody, clone OTI4H9

货号:VMA00293

规格:100μl

市场价格:3205

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原: tissue factor pathway inhibito

物种:人

宿主:小鼠

抗体亚型:IgG2a

克隆号:OTI4H9

荧光染料:Purified

产品介绍
Mouse anti Human tissue factor pathway inhibitor antibody, clone OTI4H9recognizes tissue factor pathway inhibitor, also known as anti-convertin and extrinsic pathway inhibitor.Encoded by the TFPI gene, tissue factor pathway inhibitor is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of TFPI have been described, but the full-length nature of some of these variants has not been confirmed (provided by RefSeq, Jul 2008).Mouse anti Human tissue factor pathway inhibitor antibody, clone OTI4H9 detects a band of 40-45 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationMouse monoclonal antibody purified by affinity chromatography from tissue culture supernatant.
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.09% Sodium Azide (NaN3).
ImmunogenRecombinant protein corresponding to amino acids 29-304 of human tissue factor pathway inhibitor (NP_006278) produced inE. coli
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch.
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting1/1000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.Flow CytometryUse 10ul of the suggested working dilution to label 106cells or 100ul human whole blood.
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技术参数

产品应用 wb

产品类型 单克隆抗体

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